Clinical trial · Observational
The Role of Gut Microbiome and Chronic Inflammation in Young-onset Colorectal Cancer
The Role of Gut Microbiome and Chronic Inflammation in Young-onset Colorectal Cancer: Next-generation Sequencing (NGS) as a Screening Method
NCT04011969CI-TRIAL-00039442unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study aims to investigate the role of gut microbiome pattern and inflammation marker NF-ҡB in young-onset colorectal cancer
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Blood sampling | Diagnostic Test | — | UNRESOLVED |
| Fecal sampling | Diagnostic Test | — | UNRESOLVED |
| Score assessment | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Colorectal cancer suspects
- description
- Patients suspected with colorectal cancer who come to our hospital to conduct colonoscopy procedure will be recruited for this study and will undergo a series of examinations.
- interventionNames
- Diagnostic Test: Score assessment
- Diagnostic Test: Blood sampling
- Diagnostic Test: Fecal sampling
Primary outcomes (5)
- measure
- Gut microbiome
- timeFrame
- pre-colonoscopy, approximately 1 day before colonoscopy
- description
- Gut microbiome examination will be conducted with next generation sequencing (NGS) method
- measure
- Asia Pacific Colorectal Screening (APCS) score
- timeFrame
- pre-colonoscopy, approximately 1 day before colonoscopy
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 35 Years
Show eligibility criteria text
Inclusion Criteria: 1. Age ≥ 35 years old 2. Suspected with colorectal cancer and undergoing a colonoscopy procedure 3. No history of colorectal cancer treatment Exclusion Criteria: 1. Unwilling to provide fecal and blood sample 2. Incomplete colonoscopy procedure due to any reasons
References
Publications (0)
Data not yet available
No reference posted for this study.