Clinical trial · Interventional
Acupuncture Pilot Study for Cancer-related Cognitive Function
Cancer-related Cognitive Function Acupuncture Pilot Study (CLARITY
NCT04007770CI-TRIAL-00121717active not recruitingPhase 2ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study is being done to explore whether acupuncture can improve cognitive difficulties in patients diagnosed with cancer.
Conditions
Conditions (13)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Gynecologic Cancer | Malignant Female Reproductive System Neoplasm | ALIAS | 0.90 |
| Stage I Breast Cancer | Malignant Breast Neoplasm | CURATED_BROADER | 0.78 |
| Stage I Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
| Stage I Gynecologic Cancer | Malignant Female Reproductive System Neoplasm | CURATED_BROADER | 0.78 |
| Stage II Breast Cancer | Malignant Breast Neoplasm | CURATED_BROADER | 0.78 |
| Stage II Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
| Stage II Gynecologic Cancer | Malignant Female Reproductive System Neoplasm | CURATED_BROADER | 0.78 |
| Stage III Breast Cancer | Malignant Breast Neoplasm | CURATED_BROADER | 0.78 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| 16 week waiting period + optional Acupuncture | Other | — | UNRESOLVED |
| Acupuncture | Other | — | UNRESOLVED |
| Sham Acupuncture | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- Acupuncture
- interventionNames
- Other: Acupuncture
- type
- SHAM_COMPARATOR
- label
- Sham Acupuncture (SA)
- interventionNames
- Other: Sham Acupuncture
- type
- OTHER
- label
- Wait-List Control
- description
- This arm is Closed to accrual.
- interventionNames
- Other: 16 week waiting period + optional Acupuncture
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * English-speaking * Age 18 ≥ years old * Diagnosis (breast, colorectal, prostate or gynecological cancer) * Completed initial cancer treatment (surgery, chemotherapy, and/or radiation therapy) at least one month prior to study enrollment (patients receiving maintenance cancer treatment with hormonal or targeted therapies are permitted) * Must report moderate or greater perceived CD as indicated by a score of "quite a bit" or "very much" on at least one of the two items that specifically assess concentration (item #20) and memory (item #25) on the EORTC QLQ-C30 instrument (version 3.0) * Must indicate that their cognitive functions have worsened since their cancer diagnosis by replying "Yes" to all of the following questions: * Do you think or feel that your memory or mental ability has gotten worse since your cancer diagnosis? * Do you think your mind isn't as sharp now as it was before your cancer diagnosis? * Do you feel like these problems have made it harder to function on your job or take care of things around the home? * Must be willing to adhere to all study-related procedures, including randomization to one of the 2 possible choices: acupuncture or sham acupuncture Exclusion Criteria: * Active disease * Use of acupuncture for cognitive symptom management within the past 3 months * Diagnosis of Alzheimer's disease, vascular dementia, Parkinson disease, or other organic brain disorder * Score of ≥10 on the Blessed Orientation-Memory-Concentration (BOMC) screening instrument * Primary psychiatric disorder not in remission * Initiation or change in medication (e.g., hypnotics, sedatives, and/or antidepressants) in the past 8 weeks
References
Publications (0)
Data not yet available
No reference posted for this study.