Clinical trial · Observational
The Biomarkers Of RIsk of Colorectal Cancer (BORICC) Follow-Up (BFU) Study
NCT04005742CI-TRIAL-00039283BFUcompletedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Worldwide, colorectal cancer is the 3rd most common cancer; risk increases with age and is modified by lifestyle factors notably diet, physical activity and obesity. The BORICC Follow-Up (BFU) Study is a 12+ year follow-up of participants recruited to the Biomarkers of Risk of Colon Cancer (BORICC) Study. This longitudinal study will investigate associations between ageing and lifestyle factors and a panel of molecular biomarkers linked with colorectal cancer risk.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (2)
- label
- Healthy
- description
- Participants recruited to the healthy arm of the BORICC Study (BORICC1) at baseline.
- label
- Polyp
- description
- Participants recruited to the polyp arm of the BORICC Study (BORICC2) at baseline, with a prior history of polyps.
Primary outcomes (2)
- measure
- Faecal calprotectin concentrations (marker of local inflammation)
- timeFrame
- 12 years (on average)
- measure
- Serum high-sensitivity C-Reactive Protein concentrations (marker of systemic inflammation)
- timeFrame
- 12 years (on average)
Secondary outcomes (18)
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * Took part in the BORICC Study at baseline (recruited 2005/6) Exclusion Criteria: * Unable to travel to the hospital to attend study visit * Unable to provide informed written consent
References
Publications (0)
Data not yet available
No reference posted for this study.