Clinical trial · Observational
Pain, Body Composition and Physical Activity in Childhood Cancer.
Exploring Pain, Body Composition and Physical Activity in Childhood Cancer: a Case Control Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 16, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260916-000001
Summary
Brief summary (as posted)
Comparing baseline assessments of children with cancer and their parents with baseline assessments of healthy children and their parents in a case-control study will allow the investigators to make the comparison in terms of pressure hyperalgesia, pain catastrophizing, energy-balance related behavior, attention control and attention bias between healthy children and cancer patients. This also enables the investigators to compare parents of healthy children with parents of cancer patients in the field of catastrophizing about the pain of their child and responses to child's pain experiences. Correlations can also be calculated between, for example, pain pressure thresholds and energy-balance related behavior.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Childhood Cancer | Childhood Malignant Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (2)
- label
- Childhood cancer
- description
- Children with an established cancer diagnosis (any type) between 8-18 years old that are currently being treated for cancer (not necessarily hospitalized) in the University Hospital Brussels or Ghent.
- label
- Healthy controls
- description
- Healthy children between 8-12 years old, selected based on age and sex.
Primary outcomes (1)
- measure
- Pressure hyperalgesia (child)
- timeFrame
- 1 day
- description
- Pain response to stimuli that are normally not painful, induced by the lowering of the nociceptor threshold level and assessed by evaluating pressure pain thresholds (PPTs) at the dominant tibialis anterior and trapezius muscle by means of a digital pressure algometer (FPX 50, Wagner Instruments, Greenwich, CT, USA). Per test site, 3 measurements are performed with 30 seconds between each measurement. The measurements take place alternately between the two test sites, the first test site being randomly determined by an independent blinded researcher. The pressure pain threshold in kgf per muscle (test site) is determined by the mean of the 2nd and 3rd measurement.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 8 Years
- Maximum age
- 12 Years
Show eligibility criteria text
Inclusion Criteria: All participants: * Willing to participate and comply with pre-determined interventions * 8-18y (children) * Child and parent(s)/guardian cohabited for the past 5 years or, in case of divided custody, for at least half of the child's lifetime Cancer patients * Established cancer diagnosis (any type) * First cancer diagnosis * Currently being treated for cancer (not necessarily hospitalized) in the University Hospital Brussels or Ghent Exclusion Criteria: * Developmental disabilities (e.g.: autism spectrum disorder, Attention Deficit (Hyperactivity) Disorder) * Psychiatric disorders (e.g.: anxiety disorder, personality disorder) * Significant vision or hearing impairment * Chronic pain diagnosis (e.g.: fibromyalgia, migraine, chronic abdominal pain, etc.) * Not able to read and speak fluent Dutch (parent and child) * Already having undergone any kind of self-regulation and/or behavioral therapy for pain (i.e. relaxation, hypnosis, biofeedback, pain neuroscience education, cognitive behavioral therapy, etc.)
References
Publications (0)
Data not yet available