Clinical trial · Observational
Impact of Risk for OSA in Lung Cancer
The Impact of High Risk for OSA in Prognosis and Treatment Outcomes of Lung Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Background: Previous studies have reported that intermittent hypoxia in obstructive sleep apnea (OSA) is associated with tumor progression, metastasis and treatment outcomes. However, studies explaining the relationships between specific types of cancer and OSA are needed. In this study, it is aimed to show the effect of excessive daytime sleepiness as determined by Epworth sleepiness scale(ESS) and the effect of OSA risk determined by STOP BANG questionnaire on survival and treatment outcomes in lung cancer. Method: The patients who admit the palliative care outpatient clinic of our hospital with the diagnosis of lung cancer (stage 3 and stage 4 non-small cell lung cancer or limited / extensive stage small cell lung cancer) between July 2019-2020 will be assessed for excessive daytime sleepiness(EDS) and risk of obstructive sleep apnea (OSA) by Epworth sleepiness scale and the STOP-BANG questionnaire. The patients will be grouped according to the risk of OSA and EDS.Total / progression-free survival, treatment outcomes and side effects of the treatment will be evaluated comparatively.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
| Obstructive Sleep Apnea | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| STOP- BANG Questionnaire and Epworth sleepiness scale | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- label
- Moderate/high risk for OSA with EDS
- description
- All clinical data of the patients who has moderate/high risk for OSA with excessive daytime sleepiness (EDS) will be assessed with statistical methods.
- interventionNames
- Other: STOP- BANG Questionnaire and Epworth sleepiness scale
- label
- Moderate/high risk for OSA without EDS
- description
- All clinical data of the patients who has moderate/high risk for OSA without excessive daytime sleepiness(EDS) will be assessed with statistical methods.
- interventionNames
- Other: STOP- BANG Questionnaire and Epworth sleepiness scale
- label
- Low risk for OSA
- description
- All clinical data of the patients who has low risk for OSA will be assessed with statistical methods.
- interventionNames
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * Patients between 18-75 years of age with the diagnosis of lung cancer (stage 3 and 4 non-small cell lung cancer or limited / extensive small cell lung cancer) and who sign the informed consent to participate in the study Exclusion Criteria: * Patients older than 75 years old amd younger than 18 years old * Sedatives / anxiolytic drug users * Neurological or psychiatric disorders * Those who have contradictions for standard chemoradiotherapy (ECOG performance status 3-4) * Stage 1 or stage 2 non-small cell lung cancer patients who may be referred to thoracic surgery * Patients with brain metastasis * People who have a shift work * Vena cava superior syndrome * Alcohol dependence * Malignant airway stenosis * Congestive heart failure (EF \<50%) * Patients with chronic renal failure
References
Publications (0)
Data not yet available