Clinical trial · Interventional
Endoscopic Treatment of Rectal Neuroendocrine Tumor(NET) Less Than 10mm
Cap Endoscopic Mucosal Resection(EMR-C) Versus Endoscopic Submucosal Dissection(ESD) for Treatment of Rectal Neuroendocrine Tumor(NET) Less Than 10mm
NCT03982264CI-TRIAL-00039026unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Cap-assisted endoscopic mucosal resection (EMR-C) and endoscopic submucosal dissection (ESD) have both been reported to be effective treatment methods for small rectal neuroendocrine tumor (NET) in limited studies. Which one is better has not been determined. We aimed to compare the efficacy and safety of EMR-C and ESD for the treatment of small rectal NET.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Rectal Neuroendocrine Tumor | Rectal Neuroendocrine Tumor | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| EMR-C procedure | Procedure | — | UNRESOLVED |
| ESD procedure | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- ESD group
- description
- In ESD group, enrolled patients will receive the treatment modality of ESD to remove the rectal NET
- interventionNames
- Procedure: ESD procedure
- type
- EXPERIMENTAL
- label
- EMR-C group
- description
- In EMR-C group, enrolled patients will receive the treatment modality of EMR-C to remove the rectal NET
- interventionNames
- Procedure: EMR-C procedure
Primary outcomes (1)
- measure
- complete resection rate(R0 rate)
- timeFrame
- within 14 days after procedure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * Age from 18 to 75 years; * Definite diagnosis of rectal NET less than 10mm; * Patients plan to receive either EMR-C or ESD treatment. Exclusion Criteria: * Serious comorbid diseases such as advanced malignant tumor and organ failure; * Patients received conventional EMR, snare electrotomy and no treatment; * Rectal NET with metastasis; * Pregnant patient; * Poor compliance
References
Publications (1)
- DERIVEDGao X, Huang S, Wang Y, Peng Q, Li W, Zou Y, Han Z, Cai J, Luo Y, Ye Y, Li A, Bai Y, Chen Y, Liu S, Li Y. Modified Cap-Assisted Endoscopic Mucosal Resection Versus Endoscopic Submucosal Dissection for the Treatment of Rectal Neuroendocrine Tumors </=10 mm: A Randomized Noninferiority Trial. Am J Gastroenterol. 2022 Dec 1;117(12):1982-1989. doi: 10.14309/ajg.0000000000001914. Epub 2022 Aug 23. PMID 36455222