Clinical trial · Observational
Study on the Effect of Bile Reflux on Gastric Cancer and Its Precancerous Lesions: a Cross-sectional Study.
Study on the Effect of Bile Reflux on Gastric Cancer and Its Precancerous Lesions: a Multiple Center, Cross-sectional Study.
NCT03976739CI-TRIAL-00046592completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To explore the effects of bile reflux on gastric cancer and its precancerous lesions, so as to better prevent the occurrence and development of gastric cancer.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Bile Reflux Gastritis | — | UNRESOLVED | — |
| Gastric Cancer | Malignant Gastric Neoplasm | CURATED_BROADER | 0.80 |
| Helicobacter Pylori Infection | — | UNRESOLVED | — |
| Intestinal Metaplasia | — | UNRESOLVED | — |
| Precancerous Lesions | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (3)
- label
- chronic gastritis
- description
- patients with chronic non-atrophic gastritis and chronic atrophic gastritis according to histopathological results
- label
- precancerous lesion
- description
- patients with gastric intestinal metaplasia and intraepithelial neoplasia according to histopathological results
- label
- gastric cancer
- description
- patients with gastric cancer according to histopathological results
Primary outcomes (1)
- measure
- corelation between the bile reflux and gastric mucosa diseases
- timeFrame
- up to 6 months
- description
- we evaluate the corelation between the bile reflux and gastric mucosa diseases according to the histopathological results and the scales the patients finished
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: 1. Age 18 to 75 years old, gender is not limited; 2. patients with upper abdominal pain, abdominal distension, belching, anorexia, early satiety, hiccup, acid reflux, upper abdomen burning sensation and other upper gastrointestinal symptoms; 3. Voluntary acceptance of Hp testing; 4. Voluntary acceptance of the endoscopy and pathological biopsy. Exclusion Criteria: 1. had undergone upper gastrointestinal surgery; 2. Previous diagnosis of esophageal cancer; 3. Previous diagnosis of gastric cancer; 4. Previous diagnosis of MALT lymphoma; 5. pregnant and lactating women; 6. Those with mental disorders; 7. Refusal to sign the informed consent form.
References
Publications (0)
Data not yet available
No reference posted for this study.