Clinical trial · Observational
Evaluation of the Pravalence of Rathke's Cleft Cyst of Children Under 15 Years
NCT03975712CI-TRIAL-00038948PREVA-KPRcompletedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of the study was to evaluate the pravalence of Rathke's Cleft Cyst of children under 15 years of age and demonstrate that their prevalence is higher than for patients over 15 years of age, due to their embryonic origin. It is also aimed to describe their aspect on MRI and evaluate the interobserver agreement in the detection of Rathke's Cleft Cyst.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Rathke's Cleft Cyst | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Not applicable, no intervention | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Presence or absence of a strictly intra-pituitary cystic lesion which localization and signal was compatible with an RCC, which type was defined according to its signal
- timeFrame
- All MRI performed on a period of one year in children under 15 years will be taken into account
Secondary outcomes (4)
- measure
- Maximum anteroposterior diameter (parallel to the bi-callous plane) of the cyst measured in sagittal section
- timeFrame
- All MRI performed on a period of one year in children under 15 years will be taken into account
- measure
- Cyst signal on T2-weighted spin echo sequence compared to cerebrospinal fluid (hypo / iso / hyper signal) and T1-weighted compared to cerebral white matter (hypo / iso / hyper signal)
- timeFrame
- All MRI performed on a period of one year in children under 15 years will be taken into account
- measure
- Motive for which brain MRI was performed
Eligibility
Eligibility (as posted)
Show eligibility criteria text
Inclusion Criteria: * children aged 15 or under at the time that an MRI was performed exploring the sellar region * MRI with at least T1 spin echo (SE) sagittal slices with a slice thickness of 2.5 or 3 mm with inter-slice spacing of 0.3 mm and T2 SE with a slice thickness of 2 mm and inter-slice spacing of 0.2 mm. Exclusion Criteria: * Patients with incomplete MRI protocol * Patients whose MRI images had artifacts (patient movement, presence of dental material) * Patients with suspected pituitary pathology due to endocrine symptomatology (growth retardation, puberty delay, diabetes insipidus) that could be attributed to an intrasellar injury were also excluded.
References
Publications (0)
Data not yet available
No reference posted for this study.