Clinical trial · Interventional
Bilateral Ultrasound Guided Quadratus Lumborum Versus Lumbar Epidural Block on Postoperative Analgesia, and Inflammatory Response in Abdominal Surgery
Effect of Bilateral Ultrasound Guided Quadratus Lumborum Block Versus Lumbar Epidural Block on Postoperative Analgesia, and Inflammatory Response Following Major Lower Abdominal Cancer Surgery
NCT03958942CI-TRIAL-00039348unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study aims at comparing the effects of bilateral ultrasound-guided quadratus lumborum block versus lumbar epidural block on postoperative analgesia and inflammatory response following major lower abdominal cancer surgery.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Inflammatory Response | — | UNRESOLVED | — |
| Postoperative Pain | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| lumbar epideural block with bupivacaine 25% | Other | — | UNRESOLVED |
| Ultrasound quadratus lumborum block with bupivacaine 25% | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- quadratus lumborum block
- description
- received pre-emptive ultrasound-guided quadratus lumborum block with 25 mL of 0.25% bupivacaine on each side of the abdominal wall before induction of GA.
- interventionNames
- Other: Ultrasound quadratus lumborum block with bupivacaine 25%
- type
- ACTIVE_COMPARATOR
- label
- lumbar epideural block
- description
- received pre-emptive lumbar epidural block with 15 mL of 0.25% bupivacaine before induction of GA.
- interventionNames
- Other: lumbar epideural block with bupivacaine 25%
Primary outcomes (1)
- measure
- postoperative pain
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 60 Years
Show eligibility criteria text
Inclusion Criteria: * ASA II, III * Weight 50 - 85 kg. * Scheduled for major lower abdominal cancer surgery (radical cystectomy, total abdominal hysterectomy). Exclusion Criteria: * Patients with a history of relevant drug allergy. * Coagulation disorders. * Opioid dependence. * Sepsis. * Local infection at the vicinity of the block site. * Patients with psychiatric illnesses that would interfere with perception and assessment of pain
References
Publications (0)
Data not yet available
No reference posted for this study.