Clinical trial · Observational
SUCCOR-Surgery in Cervical Cancer Comparing Different Surgical Aproaches in Stage IB1 Cervical Cancer
An International European Retrospective Cohort Observational Study Comparing Laparoscopic or Robotic Radical Hysterectomy Versus Abdominal Radical Hysterectomy in Patients With Stage IB1 (FIGO 2009) Cervical Cancer Operated in 2013-2014
NCT03958305CI-TRIAL-00038828SUCCORunknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
SUCCOR study tries to understand the outcomes of European patients with stage IB1 cervical cancer (FIGO 2009)1, that underwent a radical hysterectomy for cervical cancer in 2013-2014 within the ESGO area (European Society of Gynecologic Oncology)
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Uterine Cervical Neoplasms | Cervical Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| RADICAL HYSTERECTOMY | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- LAPAROTOMY
- description
- Radical hysterectomy by laparotomy
- interventionNames
- Procedure: RADICAL HYSTERECTOMY
- label
- MINIMALLY INVASIVE SURGERY
- description
- Radical hysterectomy by minimally invasive surgery (Laparoscopy or Robotics)
- interventionNames
- Procedure: RADICAL HYSTERECTOMY
Primary outcomes (1)
- measure
- Disease-free survival at 4.5 years
- timeFrame
- From date of surgery for cervical cancer (Radical Hysterectomy) until the date of first documented progression or date of death from any cause, whichever came first, assessed up to 84 months
- description
- Compare disease-free survival at 4.5 years in patients who underwent a laparoscopic or robotic radical hysterectomy (MIS) vs. abdominal radical hysterectomy (TARH) for stage IB1 cervical cancer.
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion criteria * Primary squamous cell carcinoma, adenocarcinoma, or adenosquamous carcinoma of the uterine cervix * Stage IB1 carcinoma, \<4 CMS, (FIGO 2009) * Preoperative pelvic MRI indicating tumor diameter \< 4 cm (at least two dimensions,) and no parametrial invasion. Exceptionally it can be considered acceptable Vaginal Ultrasound, only if your Institution have internally validated this technique for cervical cancer. Otherwise it cannot be accepted. * Preoperative either (Abdominal) CT scan or MRI or PET-CT ruling out extracervical metastatic disease * Performance status ECOG 0-1 * Age 18 years or older * Radical hysterectomy Type II-III or Type B-C by MIS (laparoscopic or robotic) or open surgery. * Patient was operated during the years 2013-2014 within the ESGO area. * Bilateral pelvic lymphadenectomy (+- sentinel LN biopsy) * Pathologic report shows information on tumor size, vaginal and parametrial margins and nodal status Exclusion criteria * No past medical history of any invasive tumor * No previous abdominal or pelvic radiotherapy of any type (including braquitherapy). * No history of preoperative neoadjuvant chemotherapy . * No cervical conization previous to surgery * No suspicious positive pelvic or paraaortic nodes or metastatic disease on PET CT, MRI, or CT. * There is none uterine diameter larger than 12cm * No Conversion from MIS to laparotomy
References
Publications (1)
- BACKGROUNDRamirez PT, Frumovitz M, Pareja R, Lopez A, Vieira M, Ribeiro R, Buda A, Yan X, Shuzhong Y, Chetty N, Isla D, Tamura M, Zhu T, Robledo KP, Gebski V, Asher R, Behan V, Nicklin JL, Coleman RL, Obermair A. Minimally Invasive versus Abdominal Radical Hysterectomy for Cervical Cancer. N Engl J Med. 2018 Nov 15;379(20):1895-1904. doi: 10.1056/NEJMoa1806395. Epub 2018 Oct 31. PMID 30380365