Clinical trial · Interventional
Evolution of the Physical Condition in Treated Cancer Patients
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Adaptated Physical Activity (APA) during treatment of cancer is one of the actual global health recommendation because of the benefits observed in several parameters evaluated in many clinical studies. A best knowledge of the physical and medical characteristics of patients, including type of cancer and type of treatment, is primordial to optimize the patient care and the effectiveness of APA programs. Descriptive, explorative and prospective study of 3 different populations: One population with locally advanced or metastatic non-small cell lung cancer treated with multiple therapeutic lines. Two different populations of early cancer patients and treated with a platinum-based regimen for colon cancer and a taxane-based chemotherapy for breast cancer.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer Female | — | UNRESOLVED | — |
| Colon Cancer | Malignant Colon Neoplasm | CURATED_EXACT | 0.92 |
| Non-small Cell Lung Cancer Metastatic | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Adaptated Physical Activity | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- experimental: observational cohort
- description
- Evaluation of the physical condition and the quality of life
- interventionNames
- Other: Adaptated Physical Activity
Primary outcomes (1)
- measure
- evolution of exercise tolerance
- timeFrame
- change from baseline exercise tolerance at 12 weeks after the end of the treatment
- description
- To describe exercise tolerance, by a six-minute walk test, in patients treated for a cancer (of lung, breast or colon) after 8 weeks of treatment.
Secondary outcomes (12)
- measure
- measurement of parameters reflecting the physical condition
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Woman with breast cancer treated with adjuvant chemotherapy (taxane) or patient with colon cancer treated with adjuvant regimen (FOLFOX) or patient with locally advanced or metastatic lung cancer * Patient without contraindication to the study-specific assessments * Eastern Cooperative Oncology Group ≤ 2 * Age ≥ 18 years old * Life expectancy \> 6 months * Able to speak, read and understand French * Written informed consent obtained from the patient * Registration in a national health care system Exclusion Criteria: * Patient with psychiatric, neurologic or musculoskeletal disorders * Pregnant or breastfeeding women * Minor or protected adult
References
Publications (2)
- DERIVEDMallard J, Hucteau E, Schott R, Pivot X, Pagano AF, Hureau TJ. Tracking cancer-related fatigue during chemotherapy: Insights from a comparative cohort study of early breast cancer patients. Int J Cancer. 2025 Oct 15;157(8):1625-1636. doi: 10.1002/ijc.35508. Epub 2025 Jun 10. PMID 40492859
- DERIVEDMallard J, Hucteau E, Schott R, Petit T, Demarchi M, Belletier C, Ben Abdelghani M, Carinato H, Chiappa P, Fischbach C, Kalish-Weindling M, Bousiniere A, Dufour S, Favret F, Pivot X, Hureau TJ, Pagano AF. Evolution of Physical Status From Diagnosis to the End of First-Line Treatment in Breast, Lung, and Colorectal Cancer Patients: The PROTECT-01 Cohort Study Protocol. Front Oncol. 2020 Aug 7;10:1304. doi: 10.3389/fonc.2020.01304. eCollection 2020. PMID 32903594