Clinical trial · Interventional
Oncotool for Cancer Medications
Feasibility of OncoTool to Improve Self-Management and Adherence to Oral Anticancer Medications
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to examine the efficacy of a psychosocial eHealth intervention on the proposed primary outcomes, TKI adherence and health related quality of life (HRQoL), in patients taking TKIs for cancer management. The intervention components include psychosocial management strategies, cancer medication knowledge and embedded physician reports. The intervention will be delivered via an online application over an 8-week period. Participants in the intervention will complete bi-weekly side effect questionnaires as part of their study involvement, which may trigger an alert to their prescribing physician if they reach a certain threshold. Participants in the control will not complete these questionnaires. Participants are randomized into either an intervention application (described above) or a control application (health information and general health promotion strategies). Aside from having access to the online application for the recommended 8 weeks, participation in this study includes three assessments: baseline (at the beginning of the research study), post-intervention (8 weeks after baseline) and a 6-month follow-up.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| Cancer, Treatment-Related | Malignant Neoplasm | ALIAS | 0.85 |
| Communication | — | UNRESOLVED | — |
| Medication Adherence | — | UNRESOLVED | — |
| Tyrosine Kinase Inhibitor | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Oncotool Control (health information) | Behavioral | — | UNRESOLVED |
| Oncotool Intervention (symptom reporting + TKI education) | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- "OncoTool" Intervention
- interventionNames
- Behavioral: Oncotool Intervention (symptom reporting + TKI education)
- type
- ACTIVE_COMPARATOR
- label
- "Oncotool" Control
- interventionNames
- Behavioral: Oncotool Control (health information)
Primary outcomes (4)
- measure
- Change in Self Reported Adherence to TKIs will be evaluated with the ARMS questionnaire.
- timeFrame
- Time Frame: T1 (prior to starting intervention), T2 (8 weeks post intervention), T3 (6 months post-intervention)
- description
- The ARMS (Adherence to Refills and Medications Scale) survey is a previously validated patient-report measure of barriers to medication adherence and adherence-related behavior.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. ≥ 18 years of age 2. medical chart confirmed diagnosis of cancer 3. willingness to be randomized into study 4. have initiated TKIs within the past 18 months, as data in literature indicates that the majority of patients who initiate oral anticancer medications are still adherent within the first few months 5. willing to use a web-based platform on a bi-weekly basis, as well as an email address and access to the internet 6. English speaking, as all material will be in English Exclusion Criteria: (a) significant cognitive impairment, inpatient psychiatric treatment, or overt signs of severe psychopathology (e.g., psychosis).
References
Publications (0)
Data not yet available