Clinical trial · Observational
CT-based Radiomic Signature Can Identify Adenocarcinoma Lung Tumor Histology
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Lung cancer remains the leading cause of cancer related mortality worldwide, with more than 1.5 million related deaths annually. Lung cancer is divided into two main groups: Small Cell Lung Carcinoma (SCLC) and Non-Small Cell Lung Carcinoma (NSCLC), with prevalence of \~20% and 80% respectively. NSCLC is further subdivided into adenocarcinoma (the most common), squamous cell carcinoma (SCC), and large cell carcinoma. Furthermore, each subtype is likely to have specific mutations, which could be targeted for treatment. Medical imaging and radiomics feature extraction represent a candidate alternative to conventional tissue biopsy, a theory that is investigated in this study.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Nonsmall Cell Lung Cancer | Lung Non-Small Cell Carcinoma | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Virtual biopsy | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (4)
- label
- Maastro (Lung1)
- description
- Open source dataset available at TCIA.org. The cohort includes CT scans of 422 patients diagnosed with NSCLC.
- interventionNames
- Diagnostic Test: Virtual biopsy
- label
- UCSF
- description
- A cohort of patients diagnosed with NSCLC at UCSF medical center. It includes CT scans of 165 patients.
- interventionNames
- Diagnostic Test: Virtual biopsy
- label
- Radboud
- description
- A cohort of patients diagnosed with NSCLC at Radboud medical center. It includes CT scans of 255 patients.
- interventionNames
- Diagnostic Test: Virtual biopsy
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * Availability of diagnostic non-contrast enhanced CT scan. * Availability of histologic tumor analysis results Exclusion Criteria: \-
References
Publications (0)
Data not yet available