Clinical trial · Observational
Ketohexokinase Isoforms in Endometrial Cancer.
Prognostic Evaluations of Ketohexokinase Isoforms in Endometrial Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Our preliminary analysis with clinical database suggested that, in patients with type I endometrial cancer, high ketohexokinase-expressing group have lower survival probabilities than low ketohexokinase-expressing group. To understand the importance of ketohexokinase expression and isoform switch during the development of type I endometrial cancer, we propose a series of in vitro experiments and clinical examinations in this project.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Endometrial Cancer | Malignant Endometrial Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| ketohexokinase | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- The role of ketohexokinase isoforms in the overall survival of endometrial cancer.
- timeFrame
- 5 years
- description
- Cox proportional hazard regression to evaluate the role of ketohexokinase isoforms in the overall survival of endometrial cancer.
Secondary outcomes (1)
- measure
- Correlation of ketohexokinase isoforms with the other prognostic risk factors
- timeFrame
- 5 years
- description
- Correlation of ketohexokinase isoforms with deep myometrial invasion, tumor grade, lymph node metastasis, FIGO stage, tumor size, progression-free survival, etc.
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 20 Years
Show eligibility criteria text
Inclusion Criteria: * \>20 years * Women with endometrial cancer who are about to be admitted to hospital for gynecological staging. * Women who have undergone gynecological staging surgery for endometrial cancer in the past. Exclusion Criteria: * Women with endometrial cancer who receive preoperative chemotherapy or radiation therapy.
References
Publications (0)
Data not yet available