Clinical trial · Interventional
Application of Raw Corn Starch on Patients With Insulinoma
Application of Raw Corn Starch on Patients With Unoperated Insulinoma is Helpful to Decrease Risk of Hypoglycemia
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This will be a prospective single-arm before-and-after clinical trial in which raw corn starch (RCS) will be first applied on patients with unoperated insulinoma. Nutritional intervention with supplementation of RCS will be initiated in 20 patients with suspected insulinoma to improve their hypoglycemia before the surgery. Duration of nutritional intervention, fasting blood glucose, lipid profile, weight change, BMI and other metabolic indices will be recorded and compared before and after the intervention.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Hyperinsulinemic Hypoglycemia | — | UNRESOLVED | — |
| Insulinoma | Pancreatic Insulinoma | ALIAS | 0.90 |
| Raw Corn Starch | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| low GI diet with regular supplementation of raw corn starch | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Intervened arm
- description
- as in a single-arm before-and after study, the only one arm will receive intervention of low GI diet with supplementation of RCS.
- interventionNames
- Other: low GI diet with regular supplementation of raw corn starch
Primary outcomes (3)
- measure
- the change of fasting blood glucose
- timeFrame
- from initiation of nutritional intervention to 2 weeks later, or by the time of curative surgery
- description
- the change of mean fasting blood glucose before and after nutritional intervention
- measure
- the change of requency of hypoglycemia onset
- timeFrame
- from initiation of nutritional intervention to 2 weeks later, or by the time of curative surgery
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * having recurrent symptoms of hypoglycemia (blood glucose less than 2.8 mmol/L) which could be relieved by intake of glucose, which condition accords with typical Whipple triad. * being proved to have abnormally increased secretion of endogeneous insulin at onset of hypoglycemia. * diagnosis of insulinoma is highly suspected, in view of clinical presentation, laboratory tests and imaging examinations. Exclusion Criteria: * severe gastrointestinal dysfunction with intolerance of raw corn starch
References
Publications (0)
Data not yet available