Clinical trial · Interventional
Assessment of Ergonomics in 3D vs 2D Thoracoscopic Lobectomy
Ergonomical Assessment of Three-Dimensional Versus Two-Dimensional Thoracoscopic Lobectomy for Lung Cancer
NCT03925103CI-TRIAL-00044555completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Video-assisted thoracic surgery (VATS) pulmonary lobectomy is currently widely employed as the first treatment option for surgical management of early stage (stage I-II) non-small-cell-lung-cancer (NSCLC). Thanks to recent technological advances in high definition display systems, three dimensional VATS (3D) has been developed in an attempt of overcoming some optical limits of two dimensional (2D) VATS. In this single center randomized trial our aim is to comparatively assess ergonomics of 3D versus 2D VATS lobectomy for early stage NSCLC.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Early Stage Non-small-cell Lung Cancer (Stage 1-2) | Lung Non-Small Cell Carcinoma | ALIAS | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| 2D VATS lobectomy | Procedure | — | UNRESOLVED |
| 3D VATS lobectomy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- 3D VATS lobectomy
- description
- Patients undergo thoracoscopic lobectomy by a three-dimensional display system
- interventionNames
- Procedure: 3D VATS lobectomy
- type
- ACTIVE_COMPARATOR
- label
- 2D VATS lobectomy
- description
- Patients undergo thoracoscopic lobectomy by a two-dimensional display system
- interventionNames
- Procedure: 2D VATS lobectomy
Primary outcomes (1)
- measure
- a difference ≥10% in the score calculated for the maneuvring ergonomical domain.
- timeFrame
- one week after surgery
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Clinical NSCLC early stage (stage I-II). * Both forced expiratory volume in one second (FEV1) and diffusion capacity of carbon monoxide (DLCO)\>60% * Both predicted postoperative (PPO) FEV1 and PPO DLCO \>35% * American Society of Anesthesia (ASA) score\<=2 * Body mass index (BMI) \>18 \<28 Exclusion Criteria: * Clinical NSCLC stage\> II * History of Neoadjuvant chemotherapy or radiotherapy * Radiologic evidence of extensive pleural adhesions. * Age \<18 or \>80 years. * Patients with previous pleurodesis or thoracotomy in the affected hemithorax. * Patients who will undergo surgical lung resection other than lobectomy. * Patients with severe comorbidity contraindicating lobectomy. * Patients refusal or noncompliance to general surgery and one-lung ventilation.
References
Publications (7)
- BACKGROUNDScott WJ, Allen MS, Darling G, Meyers B, Decker PA, Putnam JB, McKenna RW, Landrenau RJ, Jones DR, Inculet RI, Malthaner RA. Video-assisted thoracic surgery versus open lobectomy for lung cancer: a secondary analysis of data from the American College of Surgeons Oncology Group Z0030 randomized clinical trial. J Thorac Cardiovasc Surg. 2010 Apr;139(4):976-81; discussion 981-3. doi: 10.1016/j.jtcvs.2009.11.059. Epub 2010 Feb 20. PMID 20172539
- BACKGROUNDVillamizar NR, Darrabie MD, Burfeind WR, Petersen RP, Onaitis MW, Toloza E, Harpole DH, D'Amico TA. Thoracoscopic lobectomy is associated with lower morbidity compared with thoracotomy. J Thorac Cardiovasc Surg. 2009 Aug;138(2):419-25. doi: 10.1016/j.jtcvs.2009.04.026. PMID 19619789
- BACKGROUNDXu Y, Chen N, Ma A, Wang Z, Zhang Y, Liu C, Liu L. Three-dimensional versus two-dimensional video-assisted thoracic surgery for thoracic disease: a meta-analysis. Interact Cardiovasc Thorac Surg. 2017 Dec 1;25(6):862-871. doi: 10.1093/icvts/ivx219. PMID 29049786
- BACKGROUNDBagan P, De Dominicis F, Hernigou J, Dakhil B, Zaimi R, Pricopi C, Le Pimpec Barthes F, Berna P. Complete thoracoscopic lobectomy for cancer: comparative study of three-dimensional high-definition with two-dimensional high-definition video systems dagger. Interact Cardiovasc Thorac Surg. 2015 Jun;20(6):820-3. doi: 10.1093/icvts/ivv031. Epub 2015 Mar 3. PMID 25736286
- BACKGROUNDJiao P, Wu QJ, Sun YG, Ma C, Tian WX, Yu HB, Tong HF. Comparative study of three-dimensional versus two-dimensional video-assisted thoracoscopic two-port lobectomy. Thorac Cancer. 2017 Jan;8(1):3-7. doi: 10.1111/1759-7714.12387. Epub 2016 Oct 4. PMID 27755803
- BACKGROUNDDong S, Yang XN, Zhong WZ, Nie Q, Liao RQ, Lin JT, Wu YL. Comparison of three-dimensional and two-dimensional visualization in video-assisted thoracoscopic lobectomy. Thorac Cancer. 2016 Sep;7(5):530-534. doi: 10.1111/1759-7714.12361. Epub 2016 May 23.