Clinical trial · Interventional
Outcomes of Colonoscopy With Non-anesthesiologist Administered Propofol
Outcomes of Colonoscopy With Non-anesthesiologist Administered Propofol. An Equivalence Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The Efficacy and safety of Non-anesthesiologist administered propofol (NAAP) for gastrointestinal endoscopy have been widely documented although there is not information which has evaluated the outcomes of colonoscopy it self when the endoscopist has to fulfill the additional task of supervising the sedation. Objective: To determine the equivalence of adenoma detection rate (ADR) in colorectal cancer (CRC) screening colonoscopies performed with NAAP and performed with monitored anesthesia care (MAC). Method: Single blind non-randomized controlled equivalence trial. Patients: Adults between 50 - 69 years old from National CRC screening program (CRCSP). Intervention: The patients are blindly assigned to undergo either colonoscopy with NAAP or MAC according to the arrival of fecal occult blood test, patient's suitability for colonoscopy date and availability of places at endoscopy schedule (with NAAP or MAC).
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| ADR | — | UNRESOLVED | — |
| Colon Adenoma | Colon Adenoma | ONTOLOGY_EXACT | 0.98 |
| Colo-rectal Cancer | Colon Neoplasm | PROBABILISTIC | 0.70 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Sedation directed by an anesthesiologist | Procedure | — | UNRESOLVED |
| Sedation directed by an endoscopist | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Non-anesthesiologist administered propofol
- description
- Sedation directed by an endoscopist in which the intravenous drugs are propofol and fentanyl . Target level sedation: moderate - deep.
- interventionNames
- Procedure: Sedation directed by an endoscopist
- type
- ACTIVE_COMPARATOR
- label
- Monitored anesthesia care
- description
- Sedation directed by an anesthesiologist in which the used intravenous drugs and target level sedation are chosen by the anesthesiologist.
- interventionNames
- Procedure: Sedation directed by an anesthesiologist
Primary outcomes (1)
- measure
- Adenoma detection rate
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 50 Years
- Maximum age
- 69 Years
Show eligibility criteria text
Inclusion Criteria: Healthy patients - Exclusion Criteria: Patients with familial colorectal cancer history \-
References
Publications (0)
Data not yet available