Clinical trial · Interventional
Massive Implants the Next Generation
A Randomised, Single Blind Study Assessing Radiological Outcomes for Massive Segmental Femoral Replacements Using Either Porous Collar or Porous Collar With HA or Porous Collar With HA and Autologous Stem Cells
NCT03905174CI-TRIAL-00058944MINGunknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The study will review the use of massive segmental replacements in the femur, which have a porous collar with and without HA, and autologous stem cell augment. This is a randomised controlled trial.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Bone Cancer | Malignant Bone Neoplasm | ALIAS | 0.90 |
| Bone Diseases | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| custom made device | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- ACTIVE_COMPARATOR
- label
- Standard treatment
- description
- A porous collar for either distal or proximal femoral replacements
- interventionNames
- Device: custom made device
- type
- ACTIVE_COMPARATOR
- label
- standard treatment + HA
- description
- A porous collar with hydroxyapatite (HA) for either distal or proximal femoral replacements
- interventionNames
- Device: custom made device
- type
- ACTIVE_COMPARATOR
- label
- standard treatment + HA + autogenic cells
- description
- A porous collar with hydroxyapatite (HA) and stem cells for either distal or proximal femoral replacements
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Bone cancer patients requiring primary or revision femoral segmental replacements and non-cancer patients requiring revision femoral segment replacement for aseptic loosening * Male or female, aged 18 years or above * Able to provide consent Exclusion Criteria: * unable/unwilling to consent * revisions surgery due to infection * bone cancer patients excluded from stem cell arm * bone cancer patients with pathological fractures
References
Publications (0)
Data not yet available
No reference posted for this study.