Clinical trial · Observational
Rhythmic Auditory Stimulation and Walking Speed in the 6-minute Walk Test
Does Rhythmic Auditory Stimulation Influence Walking Speed in the 6-minute Walk Test in Patients With Myasthenia Gravis?
NCT03905161CI-TRIAL-00046588completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of this study is to investigate if rhythmic auditory stimulation can influence walking speed, during a 6MWT in patients with myasthenia gravis (MG).
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Myasthenia Gravis | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| 6-minute walk test | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Myasthenia patients
- description
- Danish patients with myasthenia gravis seen at the Department of Neurology, Rigshospitalet
- interventionNames
- Other: 6-minute walk test
Primary outcomes (1)
- measure
- 6-minute walk test (6MWT)
- timeFrame
- 6 minutes
- description
- The distance (meter) and walking speed (meter per seconds) in a 6-minute walk test.
Secondary outcomes (3)
- measure
- Heart rate
- timeFrame
- 5 minutes
- description
- Monitoring of heart rate by a pulse-watch prior, during (average heart rate for 6 minutes) and after the 6MWT. All three measurements are in the same units (beats per minute), and are registered directly from the pulse-watch, which the patient wear during the walk test.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Able to provide signed informed consent. * Able to read and understand Danish or English. * Diagnosis of mild to moderate MG (Able to provide signed informed consent. * Able to read and understand Danish or English. * Diagnosed with generalized mild to moderate myasthenia gravis (I-IV on the Myasthenia Gravis Foundation of American Clinical Classification, MGFA). * Documented history of acetylcholine receptor (AChR) or Muscle Specific Kinase (MuSK) antibody positive, or abnormal repetitive nerve stimulation testing (decrement \> 10%) on electromyography (EMG) or abnormal single fiber EMG (conduction block or jitter) or based on their clinical history and symptom improvement with acetylcholinesterase inhibitors. * Ability to walk \> 60 meters in a 6MWT. Exclusion Criteria: MGFA grade V disease * Other disorders that are not related to MG, or drugs, that interfere with muscle strength, walking ability, balance and fatigue (e.g. heart failure). * Serious medical illness (e.g. uncontrolled insulin dependent diabetes mellitus, symptomatic coronary artery disease, and cancer). * Dementia or pregnancy. * Unspecified reasons judged by the investigator
References
Publications (0)
Data not yet available
No reference posted for this study.