Clinical trial · Interventional
Serratus Plane Plus Pectoral I Block Versus Serratus Plane Block for Perioperative Analgesia in Breast Cancer Surgery
Does Serratus Plane Plus Pectoral I Block Provide Better Perioperative Analgesia in Ambulatory Breast Cancer Surgery When Compared to Serratus Plane Block Alone
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Breast cancer is the most common malignancy in women at worldwide. Even a minor breast surgery can cause significant postoperative pain (PP) (1). PP could be converted into chronic pain in 25-40% of cases. Inadequate PP control is associated with increased morbidity, delay in wound healing, prolonged hospital stay, increased opioid use, increased side effects and high cost of care. For these reasons, regional anesthetic techniques are recommended for effective PP management. Some of recent studies suggest that ultrasound-guided pectoral I (PI), pectoral II (PII) and serratus plan block (SPB) may be an alternative to thoracic epidural analgesia and paravertebral block applications because of the ease of administration, low side effect profile and adequate analgesia in breast surgery. (2,3).
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Narcotic Use | — | UNRESOLVED | — |
| Patient Satisfaction | — | UNRESOLVED | — |
| Postoperative Nausea | — | UNRESOLVED | — |
| Postoperative Pain | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Serratus Plane Block | Other | — | UNRESOLVED |
| Serratus Plane Block plus Pectoral I Block | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Serratus Plane Block
- description
- Serratus plane block will be applied after induction of general anesthesia.
- interventionNames
- Other: Serratus Plane Block
- type
- ACTIVE_COMPARATOR
- label
- Serratus Plane Block plus Pectoral I block
- description
- Serratus plane plus pectoral I block will be applied after induction of general anesthesia.
- interventionNames
- Other: Serratus Plane Block plus Pectoral I Block
Primary outcomes (1)
- measure
- Pain intensity score
- timeFrame
- 24 hour
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 20 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: 1. ASA 1-2-3 2. Patients scheduled for elective surgery Exclusion Criteria: 1. Previous neurological disease symptom (TIA, syncope, dementia, etc.) 2. Allergy to drugs 3. Major cardiac disease 4. Renal failure 5. Psychiatric disease 6. Patients who refuse to participate in the study
References
Publications (1)
- DERIVEDYesiltas S, Turkoz A, Calim M, Yilmaz S, Esen A, Daskaya H, Karaaslan K. Comparison of serratus plane block alone and in combination with pectoral type 1 block for breast cancer surgery: a randomized controlled study. Hippokratia. 2021 Jan-Mar;25(1):8-14. PMID 35221650