Clinical trial · Interventional
Preoxygenation With a High-flow Nasal Cannula or a Simple Mask Before General Anesthesia in Head and Neck Surgery
Comparison of Preoxygenation With a High-flow Nasal Cannula and a Simple Mask Before Intubation During Induction of General Anesthesia in Patients Undergoing Head and Neck Surgery
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Objectives: To assess arterial oxygen partial pressure (PaO2) at defined time points during the preoxygenation and to compare between high flow heated humidified nasal oxygen versus standard preoxygenation with oxygen insufflation via face mask over at least 5 minutes Methods: This randomized, single-blinded, prospective study was conducted at Asan Medical Center in Seoul, Republic of Korea. Populations: Patients undergoing head and neck surgery Expected outcomes: The course of PaO2 levels is superior to those of the face mask during the whole preoxygenation procedure and after the intubation.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Head and Neck Neoplasm | Head and Neck Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| High-flow nasal cannula | Device | — | UNRESOLVED |
| simple mask | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Group N
- description
- pre-oxygenation with High-flow nasal cannula
- interventionNames
- Device: High-flow nasal cannula
- type
- ACTIVE_COMPARATOR
- label
- Group M
- description
- pre-oxygenation with simple mask
- interventionNames
- Device: simple mask
Primary outcomes (1)
- measure
- PaO2 (arterial oxygen partial pressure) at pre-defined time points.
- timeFrame
- through study completion, an average of 10 minutes
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 19 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: 1. Patients with head and neck cancer undergoing resection surgery planned arterial cannulation and invasive arterial blood pressure monitoring and arterial blood gas analysis 2. Patients over 19-year old 3. Patients who voluntarily participated in the study 4. Patents in American Society of Anesthesia physical status 1-3 Exclusion Criteria: 1. Patients who don't approve to participation 2. Unable to give informed consent because of a language barrier 3. Patients with severe respiratory disease 4. Patients with severe cardiovascular or cerebrovascular disease 5. Patients with severe psychiatric disorders 6. Anyone who is not appropriate according to researcher's decision
References
Publications (1)
- DERIVEDJo JY, Kim WJ, Ku S, Choi SS. Comparison of preoxygenation with a high-flow nasal cannula and a simple mask before intubation during induction of general anesthesia in patients undergoing head and neck surgery: Study protocol clinical trial (SPIRIT Compliant). Medicine (Baltimore). 2020 Mar;99(12):e19525. doi: 10.1097/MD.0000000000019525. PMID 32195955