Clinical trial · Observational
Real World Study of Lapatinib Among Metastatic Breast Cancer Patients
Real World Study of Lapatinib Among Metastatic Breast Cancer Patients in Clinical Practice: a Multicenter, Retrospective Study
NCT03894410CI-TRIAL-00074375completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
A multicenter, retrospective, real world study of Lapatinib among Metastatic Breast Cancer (MBC) Patients in Clinical Practice.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (4)
- label
- Continuing Lapatinib
- description
- Patients continued using treatment containing Lapatinib after progression on Lapatinib.
- label
- Change HER-2 treatment
- description
- Patients changed to another HER-2 targeted treatment after progression on Lapatinib (ado-trastuzumab emtansine, trastuzumab, etc.).
- label
- Lapatinib plus capetabine
- description
- Patients used lapatinib plus capetabine.
- label
- Lapatinib plus Trastuzumab and one chemotherapy
- description
- Patients used lapatinib plus trastuzumab and one chemo regimen.
Primary outcomes (2)
- measure
- PFS
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients who were treated with Lapatinib between June 2014 to June 2018. * Patients experienced progression on prior trastuzumab-containing regimens and a taxane. * Complete medical history was available. Exclusion Criteria: * Medical history was incomplete.
References
Publications (0)
Data not yet available
No reference posted for this study.