Clinical trial · Observational
Characteristics of Gut Microbiota in Patients With Colon Cancer of Different Traditional Chinese Medicine Syndromes
Correlation Analysis of TCM Syndromes, TCM Constitution Types, Intestinal Microbial Evolution and Tumor Biological Characteristics in Colorectal Cancer Patients Before and After Surgery
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Guided by the idea of combining disease differentiation with syndrome differentiation in traditional Chinese medicine, this study used the form of questionnaire to summarize the changes of TCM syndromes, TCM constitution types in colorectal cancer patients before and after surgery. The Next-generation sequencing technology was used to explore the changes and differences of intestinal microorganisms before and after surgery. The correlation between changes of TCM syndromes, TCM constitution types, intestinal microbial evolution and tumor biological characteristics in colorectal cancer patients before and after surgery was analyzed. To explore the rationality of TCM in the prevention and treatment of colorectal cancer recurrence and metastasis in order to guide the individualized treatment and dietary regulation of TCM.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Neoplasms | Colorectal Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| No intervention | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- label
- before surgery
- description
- no intervention(s)
- interventionNames
- Other: No intervention
- label
- after surgery
- description
- no intervention(s)
- interventionNames
- Other: No intervention
- label
- Normal colonoscopy
- description
- People who were diagnosed by colonoscopy without colorectal cancer.
- interventionNames
- Other: No intervention
Primary outcomes (2)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 40 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: 1. Preoperative abdominal CT, colonoscopy and pathological examination were diagnosed as colorectal malignant tumor patients; 2. Having surgical indications; 3. Patients who were not treated with antibiotics or microbiological agents one week before surgery; 4. Patients who had not received radiotherapy and chemotherapy before surgery; 5. Patients or their legal representatives informed and agreed to participate in this clinical trial and signed a written informed consent; Exclusion Criteria: 1. Have other cancer history; 2. Patients who have received invasive treatment within the past three months; 3. Inflammatory bowel disease such as ulcerative colitis or crohn's disease; 4. Combined with intestinal obstruction or intestinal perforation for emergency surgery; 5. Psychiatric history, can not join and standardize the completion of clinical investigators; 6. Pregnant or nursing women; 7. Patients treated with antibiotics or microbiological agents one week before surgery; 8. People have incomplete data;
References
Publications (0)
Data not yet available