Clinical trial · Observational
Incidence and Risk of Influenza in Myasthenic Patients
Incidence and Risk of Influenza in Myasthenic Patients Hospitalized in Intensive Care
NCT03884777CI-TRIAL-00037722completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Upper respiratory infection , including influenza, may exacerbate the symptoms of myasthenia gravis (MG), which is an autoimmune disease that causes muscle weakness and, in some cases, can precipitate a myasthenic crisis In the present study, we investigated the incidence and risk factors of influenza infection on in myasthenia gravis patients.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Myasthenic Crisis | — | UNRESOLVED | — |
| Upper Respiratory Infection | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Incidence of influenza in myasthenic patient in crisis
- timeFrame
- between January 1, 2009 and December 31, 2017.
- description
- Number of influenza cases in myasthenic patients
Secondary outcomes (1)
- measure
- Risk factors for poor outcomes
- timeFrame
- between January 1, 2009 and December 31, 2017.
- description
- To identify risk factors for severe influenza in myasthenic patients
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Men or women over the age of 18. * Myasthenic patients hospitalized in intensive care. * Patients with confirmed influenza infection Exclusion Criteria: * Age \<18 years, * Other neuromuscular diseases, * Patient opposing the use of his data
References
Publications (4)
- RESULTPetrova VN, Russell CA. The evolution of seasonal influenza viruses. Nat Rev Microbiol. 2018 Jan;16(1):60. doi: 10.1038/nrmicro.2017.146. Epub 2017 Nov 7. PMID 29109554
- RESULTTackenberg B, Schneider M, Blaes F, Eienbroker C, Schade-Brittinger C, Wellek A, Deschauer M, Eickmann M, Klenk HD, Muller HH, Sommer N. Acetylcholine Receptor Antibody Titers and Clinical Course after Influenza Vaccination in Patients with Myasthenia Gravis: A Double-Blind Randomized Controlled Trial (ProPATIent-Trial). EBioMedicine. 2018 Feb;28:143-150. doi: 10.1016/j.ebiom.2018.01.007. Epub 2018 Jan 10. PMID 29337134
- RESULTFriman G, Schiller HH, Schwartz M. Distubed neuromuscular transmission in viral infections. Scand J Infect Dis. 1977;9(2):99-103. doi: 10.3109/inf.1977.9.issue-2.08. PMID 197596
- RESULTRosciszewska D, Bluszcz M, Kurek H. [Antibodies for DNA and RNA viruses in the serum of myasthenia patients. Preliminary report]. Neurol Neurochir Pol. 1981 Sep-Dec;15(5-6):541-4. Polish. PMID 6281675