Clinical trial · Observational
Mental Health of Men Before and After Testicular Cancer Treatment
Mental Health of Men Before and After Testicular Cancer Treatment. Danish: "Mænds Mentale Sundhed før og Efter Behandling af testikulær kræft"
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is a prospective observational study, that investigates men diagnosed with testicular cancer before and after treatment. The patients are included at their visit at the Fertility clinic in Horsens, where they deposit semen for cryopreservation prior to surgery and potential systemic treatment. Here the patients, who want to participate will perform a cognitive test and afterwards complete a questioner (T1). After 9 month the patients will be invited to perform the cognitive test and complete the questionnaire again (T2).
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cognitive Impairment | — | UNRESOLVED | — |
| Sexual Dysfunction | — | UNRESOLVED | — |
| Testis Cancer | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (7)
- measure
- Cognitive Performance, CANTAB iPad based cognitive performance test.
- timeFrame
- 9 months. The patients complete the cognitive test at baseline (T1) and again after 9 months (T2).
- description
- The cognitive test is performed on an iPad using the validated Cambridge Neuropsychological Test Automated Battery (CANTAB) Connect Research software. The cognitive domains assessed are sensorimotor function and comprehension, processing and psychomotor speed, sustained attention, visual episodic memory, working memory and strategy, visual working memory and planning, each at T1 and T2. Comparison of test results from T1 and T2 will assess if there is a change in the cognitive performance.
- measure
- Change in Self reported Cognitive Performance
- timeFrame
- 9 months. The patients complete the questionnaire at baseline (T1) and again after 9 months (T2).
- description
- Assessed by The Patients Assessment of Own Functioning Inventory (PAOFI)
- measure
- Change in Sexual Health
- timeFrame
- 9 months. The patients complete the questionnaire at baseline (T1) and again after 9 months (T2).
Eligibility
Eligibility (as posted)
- Sex
- Male
- Minimum age
- 18 Years
- Maximum age
- 45 Years
Show eligibility criteria text
Inclusion Criteria: * Men aged 18 - 45 years. * Newly diagnosed testicular cancer and referred to the fertility clinic in Horsens fore cryopreservation of semen prior to further treatment. Exclusion Criteria: * Men, who cannot talk, read ore write Danish. * Men who are not able to give informed consent.
References
Publications (1)
- DERIVEDHojris NF, Frederiksen Y, Agerbaek M, Nielsen SH, Holt M, Brand SL, Petersen NL, Knudsen UB, Amidi A. Longitudinal assessment of cognitive function in testicular cancer patients prior to orchiectomy and 9 months later and associations with tumor markers. Support Care Cancer. 2025 Jun 17;33(7):591. doi: 10.1007/s00520-025-09637-w. PMID 40526183