Clinical trial · Observational
Satisfaction & Efficacy of Compression Using Surgical Gloves in Chemo-induced Peripheral Neuropathies
Prospective Monocentric Study Evaluating Patients' Satisfaction and Efficacy of Compression Using Surgical Gloves in Peripheral Neuropathies Induced by Taxane or Platinum-based Chemotherapies
NCT03872908CI-TRIAL-00073307ELEGANTunknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Evaluation of Satisfaction \& Efficacy of Compression Using Surgical Gloves in Peripheral Neuropathies Due to Chemotherapy
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Chilled gloves | Device | — | UNRESOLVED |
| Surgical gloves | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Cohort 1
- description
- Evaluation of patient's satisfaction when wearing surgical gloves (dominant hand) versus chilled gloves (non-dominant hand) at the end of paclitaxel administration.
- interventionNames
- Device: Chilled gloves
- Device: Surgical gloves
- label
- Cohort 2
- description
- Evaluation of the efficacy of the compression induced by surgical gloves against peripheral neuropathies in patients treated by oxaliplatine after a 595 mg/m2 cumulated dose.
- interventionNames
- Device: Surgical gloves
Primary outcomes (2)
- measure
- Cohort1:Evaluation of patient's satisfaction when wearing surgical gloves (dominant hand) and chilled gloves (non-dominant hand) at the end of paclitaxel administration.
- timeFrame
- At the end of paclitaxel administration (4 to 6 months after inclusion)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Age \>= 18 years old * Breast cancer requiring a treatment by paclitaxel or colorectal cancer requiring a treatment by oxaliplatine * At least 8 chemotherapy cycles planned * Able to understand, read and write French language * Covered by a social insurance * Dated and signed informed consent Exclusion Criteria: * Pre-existing neuropathy or history of neuropathy * Psychological, family, sociological or georgraphical condition that may potentially compromise the adherence to study protocol and follow up * Cohort 1: Patients presenting a Raynaud's syndrome (contra-indication to cold temperatures) * Participation to clinical trial which may interfere with the evaluation of the main endpoints. * Pregnant or breastfeeding women
References
Publications (1)
- DERIVEDHanvic B, Joureau-Chabert A, Ouldbey Y, Toussaint P, Chanel E, Blanc E, Heudel P, Montagnier V, Perol D, Bachelot T. Compression therapy with surgical gloves compared to cold therapy with frozen gloves in preventing paclitaxel-induced peripheral neuropathy: Results from the prospective ELEGANT trial in patients with breast cancer. Eur J Cancer. 2025 Oct 16;229:115791. doi: 10.1016/j.ejca.2025.115791. Epub 2025 Sep 12. PMID 40961808