Clinical trial · Observational
Under- and Overdiagnosis in BreastScreen Norway
NCT03852953CI-TRIAL-00080255completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This PhD project will describe tumour characteristics and survival associated with of under- and overdiagnosed breast cancers, the rate of overdiagnosis in BreastScreen Norway, and whether women and family doctors are aware of, and knowledgeable about, under- and overdiagnosis in breast cancer screening.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Screening | Other | — | UNRESOLVED |
| Under- or overdiagnosed cancer | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- label
- Study 1: Under- and overdiagnosed group
- description
- Non-proportional stratified sample of women diagnosed with interval or screen-detected breast cancers after participation in BreastScreen Norway. This sample will include under- or overdiagnosed cancers, as well as cancers that were not under- or overdiagnosed.
- interventionNames
- Other: Under- or overdiagnosed cancer
- label
- Study 2: Rate of overdiagnosis group
- description
- Women residing in Norway, born between 1927 and 1934 (inclusive). This cohort will include women who have attended screening and who have not attended screening.
- interventionNames
- Other: Screening
- label
- Study 3: Awareness and knowledge group
- description
- Women aged 50-69, and practising family doctors aged 25-75, currently living in Norway.
Primary outcomes (8)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 25 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Study 1 Inclusion Criteria: * Breast cancer diagnosed within BreastScreen Norway using digital mammography * Prior screening images available for review Study 2 Inclusion Criteria: * Women born between 1927 and 1934 (inclusive) * Legal resident in Norway at any time between 1996 and 2003 (inclusive) Study 3 Inclusion Criteria: * Women residing in Norway, aged 50-69 (inclusive) * Practising family doctors in Norway, aged 25-75 (inclusive) * Provide informed consent
References
Publications (3)
- BACKGROUNDHovda T, Tsuruda K, Hoff SR, Sahlberg KK, Hofvind S. Radiological review of prior screening mammograms of screen-detected breast cancer. Eur Radiol. 2021 Apr;31(4):2568-2579. doi: 10.1007/s00330-020-07130-y. Epub 2020 Oct 1. PMID 33001307
- RESULTTsuruda KM, Hovda T, Bhargava S, Veierod MB, Hofvind S. Survival among women diagnosed with screen-detected or interval breast cancer classified as true, minimal signs, or missed through an informed radiological review. Eur Radiol. 2021 May;31(5):2677-2686. doi: 10.1007/s00330-020-07340-4. Epub 2020 Nov 12. PMID 33180162
- RESULTTsuruda KM. Overdiagnosis and 'underdiagnosis' in BreastScreen Norway [dissertation]. [Oslo, Norway]: University of Oslo; 2021. 108 p. Available at: http://urn.nb.no/URN:NBN:no-91337