Clinical trial · Interventional
Survival Outcome After Minilaparotomy for the Treatment of Colorectal Cancer
NCT03843398CI-TRIAL-00037144SoMiniCRCunknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The primary aim of this study is \- to determine the difference of survival outcome (3-year overall survival, 3y OS) between after minilaparotomy and after laparoscopy.. Other aims include to determine the data below when minilaparotomy and laparoscopy are compared with each other. * 3-year disease free survival, 3y DFS * 5-year overall survival, 5y OS * 5-year disease free survival, 5y DFS * Local recurrence rate, LRR * Postoperative complications Incidence and mortality at 30 days
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Colorectal cancer resection via minilaparotomy | Procedure | — | UNRESOLVED |
| Laparoscopic colorectal cancer resection | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Minilaparotomy Group
- description
- Participants in this arm undergo colorectal cancer resection via minilaparotomy.
- interventionNames
- Procedure: Colorectal cancer resection via minilaparotomy
- type
- ACTIVE_COMPARATOR
- label
- Laparoscopy Group
- description
- Participants in this arm undergo laparoscopic colorectal cancer resection.
- interventionNames
- Procedure: Laparoscopic colorectal cancer resection
Primary outcomes (1)
- measure
- 3-year overall survival, 3y OS
- timeFrame
- 3 years after the follow up of the last patient enrolled.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Colorectal cancer with pathological results. * Colorectal cancer preliminary diagnosed during colonoscopy. * No confirmed metastasis. * No comorbidity of other malignancy. * The primary tumor is less than 10 cm. * No organ dysfunction. * The patient and his families totally agree with the whole investigative procedure, and sign the written informed consent form. Exclusion Criteria: * Diagnosed with any other malignancy within 5 years. * Comorbidity of emergent conditions like perforation. * Former colorectal surgery history which may affects digestive tract reconstruction. * Need combined organ resection. * ASA grade IV or V. * Pregnant or lactating Women. * Severe mental diseases. * Severe cardiopulmonary diseases which reduce operation tolerance. * Systematic steroid therapy lasting for more than 1 month. * Intolerant of laparoscopy. * No written informed consent form signed.
References
Publications (2)
- BACKGROUNDWang XD, Huang MJ, Yang CH, Li K, Li L. Minilaparotomy to rectal cancer has higher overall survival rate and earlier short-term recovery. World J Gastroenterol. 2012 Oct 7;18(37):5289-94. doi: 10.3748/wjg.v18.i37.5289. PMID 23066325
- BACKGROUNDIshida H, Ishiguro T, Ohsawa T, Okada N, Kumamoto K, Ishibashi K, Haga N, Yokoyama M, Nakada H, Gonda T. Oncologic outcome of stages II/III colon cancer treated via minilaparotomy. Int Surg. 2011 Apr-Jun;96(2):127-34. doi: 10.9738/1384.1. PMID 22026303