Clinical trial · Observational
Early Palliative Care on Quality of Life of Patients With Advanced Pancreas Cancer
The Impact of Early Palliative Care on the Quality of Life of Patients With Advanced Pancreas Cancer: A Case-crossover Study
NCT03837132CI-TRIAL-00056284completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The primary objective is to explore the impact of early palliative care on quality of life in patients with advanced pancreatic cancer. The secondary objectives are to explore the impact of early palliative care on symptom management, depression, anxiety and survival in patients with advanced pancreatic cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Advanced Cancer | Malignant Neoplasm | CURATED_BROADER | 0.78 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Palliative care assessment | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Advanced pancreatic cancers
- description
- Newly diagnosed patients with advanced pancreatic cancer
- interventionNames
- Behavioral: Palliative care assessment
Primary outcomes (1)
- measure
- Impact of early palliative care on quality of life in patients with advanced pancreatic cancer
- timeFrame
- registration to 16 weeks
- description
- For the primary endpoint, we will use a generalized linear model to test for a statistically significant change score between baseline and 16 weeks. We will assume a normal distribution for the change scores. Model fit will be assessed via a visual assessment of residuals and the ratio of the model deviance to its degrees of freedom.
Secondary outcomes (1)
- measure
- To explore the impact of early palliative care on symptom management, depression, anxiety and survival in patients with advanced pancreatic cancer
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * age \>18 * newly diagnosed advanced pancreatic cancer (APC) * English speaking or willing to be seen with a medical interpreter * willing and able to complete quality of life (QoL) questionnaires Exclusion Criteria: * age \<18 * receiving cycle 2 of chemotherapy
References
Publications (1)
- DERIVEDKim CA, Lelond S, Daeninck PJ, Rabbani R, Lix L, McClement S, Chochinov HM, Goldenberg BA. The impact of early palliative care on the quality of life of patients with advanced pancreatic cancer: The IMPERATIVE case-crossover study. Support Care Cancer. 2023 Apr 6;31(4):250. doi: 10.1007/s00520-023-07709-3. PMID 37022483