Clinical trial · Interventional
A Research Program Targeting Pre- and Peri-transplant Optimization Program (R-PPOP)
NCT03823651CI-TRIAL-00081149completedN/AResults postedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to evaluate the feasibility and outcomes of a research pre- and peri-transplant optimization program (R-PPOP) to improve multiple domains of health including physical function, cognitive function, mental health, and diet and nutrition for patients planning to undergo or undergoing hematopoietic stem cell transplantation (HCT).
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Hematologic Malignancy | Hematopoietic and Lymphoid Cell Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (4)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Interval training | Behavioral | — | UNRESOLVED |
| Nutrition/diet evaluation | Behavioral | — | UNRESOLVED |
| Psychiatric consult | Behavioral | — | UNRESOLVED |
| Referral to Social Worker | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Patient
- description
- These are patients undergoing hematopoetic stem cell transplant. Patients will complete Interval training, undergo psychiatric consult, nutrition/diet evaluation and referral to social worker.
- interventionNames
- Behavioral: Interval training
- Behavioral: Psychiatric consult
- Behavioral: Nutrition/diet evaluation
- Behavioral: Referral to Social Worker
- type
- EXPERIMENTAL
- label
- Caregiver
- description
- These are the assigned caregivers for transplant patients. Caregivers will undergo psychiatric consult, nutrition/diet evaluation and referral to social worker.
- interventionNames
- Behavioral: Psychiatric consult
- Behavioral: Nutrition/diet evaluation
- Behavioral: Referral to Social Worker
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Patient Inclusion Criteria: * Plan to undergo an allogeneic hematopoietic stem cell transplant for any cancer or non-cancer illness within the next 6 months * Age 18-80 years Patient Exclusion Criteria: * Both patient and caregiver are unable to read and follow directions in English (ok if only patient cannot read and follow directions in English as caregiver will be able to help). * Any absolute contraindications to exercise: * recent (\< 6 months) acute cardiac event; * unstable angina; * uncontrolled dysrhythmias causing symptoms or hemodynamic compromise; * symptomatic aortic stenosis; * uncontrolled symptomatic heart failure; * acute pulmonary embolus; * acute myocarditis or pericarditis; * suspected or known dissecting aneurism; or * coronary artery disease. * Functional impairment resulting in inability to exercise Caregiver inclusion criteria * Identified by patient as their primary caregiver * Age 18-80 years Caregiver exclusion criteria * None
References
Publications (0)
Data not yet available
No reference posted for this study.