Clinical trial · Observational
Comprehensive Study of Social Representation of Platelet Transfusion in Patients Followed for Advanced Hematological Malignancies (R-PLQ)
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Limited data is available for end of life care in hematologic malignancies, moreover with thrombocytopenic patients. Thrombopenia is a frequent complication, specific of bone marrow involvement in those diseases or its treatments. Yet, a few studies was interested in, whereas platelet transfusion is the only treatment indicated. As it represent a scarce, limited resource, the ethical principles are in conflict in this setting and there's a lack of recommendation. The final decision is take by the clinician and his patient, but no study exist in representation of the two parts. We provide a qualitative study to understand what this decision is made of.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Hematological Malignancy | Hematopoietic and Lymphoid Cell Neoplasm | PROBABILISTIC | 0.70 |
| Palliative Care | — | UNRESOLVED | — |
| Platelet Transfusion | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| multi method questionary (developped by De Rosa, in 1995 and 2014) | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- label
- patient
- description
- patient with advanced, non curative hematological malignancies multi method questionary, at least 1 hour per patient
- interventionNames
- Other: multi method questionary (developped by De Rosa, in 1995 and 2014)
- label
- hematologist
- description
- medical practitioner of platelet transfusion multi method questionary, at least 1 hour per hematologist
- interventionNames
- Other: multi method questionary (developped by De Rosa, in 1995 and 2014)
- label
- Nurses
- description
- nurses working in hematology, practicing platelet transfusion multi method questionary, at least 1 hour per nurse
- interventionNames
- Other: multi method questionary (developped by De Rosa, in 1995 and 2014)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 100 Years
Show eligibility criteria text
Inclusion Criteria: * major patient * patient with advanced hematological malignancies * patient transfused in platelet regularly (3 time at least in last month) * medical practioner, hematologist, prescribing platelet transfusion at least one per week. * nurse working in hematology, practicing platelet transfusion at lest one peer week. Exclusion Criteria: * minor patient * non communicant patient * non transfused platelet patient * non voluntary patient or hematologist or nurses * non graduated hematologist
References
Publications (3)
- BACKGROUNDMcGrath P, Leahy M. Catastrophic bleeds during end-of-life care in haematology: controversies from Australian research. Support Care Cancer. 2009 May;17(5):527-37. doi: 10.1007/s00520-008-0506-1. Epub 2008 Sep 23. PMID 18810505
- BACKGROUNDMcGrath P, Holewa H. Special considerations for haematology patients in relation to end-of-life care: Australian findings. Eur J Cancer Care (Engl). 2007 Mar;16(2):164-71. doi: 10.1111/j.1365-2354.2006.00745.x. PMID 17371426
- BACKGROUNDJeoffrion C, Dupont P, Tripodi D, Roland-Levy C. [Social representations of illness: Comparison of "expert" knowledge and "naive" knowledge]. Encephale. 2016 Jun;42(3):226-33. doi: 10.1016/j.encep.2015.12.007. Epub 2016 Jan 12. French. PMID 26796561