Clinical trial · Interventional
Short Course Radiation Therapy in Palliative Treatment of Head and Neck Cancer
SHort Course Accelerated RadiatiON Therapy (SHARON) in Palliative Treatment of Head and Neck Cancer: an Interventional, Randomized, Multicentric Study
NCT03804073CI-TRIAL-00036694unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Aim of the study is to assess efficacy of a short course radiation treatment in patients with symptomatic head and neck (H\&N) malignant lesions
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Head and Neck Cancer | Malignant Head and Neck Neoplasm | ALIAS | 0.90 |
| Palliative Care | — | UNRESOLVED | — |
| Radiotherapy | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| short course treatment | Radiation | — | UNRESOLVED |
| standard treatment | Radiation | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- standard treatment
- description
- patients in this group are treated with 3000 cGy in 10 daily fraction
- interventionNames
- Radiation: standard treatment
- type
- EXPERIMENTAL
- label
- short course treatment
- description
- patients in this group are treated with 2000 cGy in 4 fractions administered twice a day (at least 6-8 hours interval)
- interventionNames
- Radiation: short course treatment
Primary outcomes (1)
- measure
- Efficacy of palliation using the short course scheme compared with the standard scheme
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * symptomatic H\&N malignant lesions (primary solid tumors or metastases from solid tumor) * age\>18 years * Eastern Cooperative Oncology Group (ECOG) Performance Status 0-3 * no changes in supportive care in the week before radiotherapy Exclusion Criteria: * pregnancy * previous irradiation of the same region
References
Publications (0)
Data not yet available
No reference posted for this study.