Clinical trial · Interventional
Sarcopenia and Risk of Falls in Patients With Major Chronic Diseases
Sarcopenia and Risk of Falls in Patients With Major Chronic Diseases - Effects of Therapeutic Exercise and Nutrition Intervention
NCT03798418CI-TRIAL-00061869completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The objective of this study is to investigate the effects of therapeutic exercise and nutrition intervention for sarcopenia and risk of falls in patients with major chronic diseases. The outcomes will be analyzed regarding muscle strength, quality, and volume, etc., balance and gait, bone density, body composition, fall and quality of life after the intervention.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| Chronic Kidney Diseases | — | UNRESOLVED | — |
| Osteoporosis | — | UNRESOLVED | — |
| Stroke | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| diet counseling | Dietary Supplement | — | UNRESOLVED |
| elastic band strengthening exercise | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- exercise group
- description
- elastic band strengthening exercise
- interventionNames
- Behavioral: elastic band strengthening exercise
- type
- EXPERIMENTAL
- label
- exercise combine diet counseling group
- description
- elastic band strengthening exercise combined diet counseling.
- interventionNames
- Behavioral: elastic band strengthening exercise
- Dietary Supplement: diet counseling
Primary outcomes (19)
- measure
- Change of walking speed
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
* Inclusion Criteria: 1. 55-85 years old 2. 3-6 months after onset 3. walk independently for at least 10m * Exclusion Criteria: 1. lower limb Brunnstrom stage \>5 2. combine other neuropathy diseases 3. significant deformity of lower limb include: Modified Ashworth scale(MAS) \>3; contracture, fracture, chronic joint pain. 4. joint arthroplasty 5. unstable vital sign 6. can not cooperate study
References
Publications (7)
- BACKGROUNDBiolo G, Cederholm T, Muscaritoli M. Muscle contractile and metabolic dysfunction is a common feature of sarcopenia of aging and chronic diseases: from sarcopenic obesity to cachexia. Clin Nutr. 2014 Oct;33(5):737-48. doi: 10.1016/j.clnu.2014.03.007. Epub 2014 Mar 29. PMID 24785098
- BACKGROUNDStapleton T, Ashburn A, Stack E. A pilot study of attention deficits, balance control and falls in the subacute stage following stroke. Clin Rehabil. 2001 Aug;15(4):437-44. doi: 10.1191/026921501678310243. PMID 11518445
- BACKGROUNDHyndman D, Ashburn A, Stack E. Fall events among people with stroke living in the community: circumstances of falls and characteristics of fallers. Arch Phys Med Rehabil. 2002 Feb;83(2):165-70. doi: 10.1053/apmr.2002.28030. PMID 11833018
- BACKGROUNDKutner NG, Zhang R, Huang Y, Wasse H. Falls among hemodialysis patients: potential opportunities for prevention? Clin Kidney J. 2014 Jun;7(3):257-63. doi: 10.1093/ckj/sfu034. Epub 2014 Apr 15. PMID 25852886
- BACKGROUNDCook WL, Tomlinson G, Donaldson M, Markowitz SN, Naglie G, Sobolev B, Jassal SV. Falls and fall-related injuries in older dialysis patients. Clin J Am Soc Nephrol. 2006 Nov;1(6):1197-204. doi: 10.2215/CJN.01650506. Epub 2006 Aug 30. PMID 17699348
- BACKGROUNDCouch ME, Dittus K, Toth MJ, Willis MS, Guttridge DC, George JR, Barnes CA, Gourin CG, Der-Torossian H. Cancer cachexia update in head and neck cancer: Definitions and diagnostic features. Head Neck. 2015 Apr;37(4):594-604. doi: 10.1002/hed.23599. Epub 2014 Mar 25. PMID 24415363
- BACKGROUNDLiu CJ, Latham NK. Progressive resistance strength training for improving physical function in older adults. Cochrane Database Syst Rev. 2009 Jul 8;2009(3):CD002759. doi: 10.1002/14651858.CD002759.pub2.