Clinical trial · Interventional
Does Myomectomy for Intramural Fibroid Improve ART Outcome?
Does Myomectomy for Intramural Fibroid Improve ART Outcome? A Randomized Controlled Trial
NCT03796130CI-TRIAL-00042294MIFARTunknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Intamural fibroids (myoma) do exist in some infertile women undergoing IVF treatment. There is controversy whether myomectomy before IVF treatment could improve IVF outcome. This trial will examine whether myomectomy in those patients could improve the results.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Fibroid Uterus | Uterine Corpus Leiomyoma | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Myomectomy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- (A)Myomectomy
- description
- This study will include women who have intramural myomas ranging from 3-5 cm The participants will be randomlyallocated intotwo groups. In group (A): myomectomy will be performed before ART In group 1, ART will be performed 3 months after myomectomy if the uterine cavity is not opened and 6 months after myomectomy upon inadvertent opening of the uterine cavity during surgery
- interventionNames
- Procedure: Myomectomy
- type
- NO_INTERVENTION
- label
- (B) No myomectomy
- description
- This study will include women who have intramural myomas ranging from 3-5 cm The participants will be randomly allocated into two groups. In group (B):women will have their trial of ART without myomectomy
Primary outcomes (1)
- measure
- The primary outcome will be ongoing pregnancy rate
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 35 Years
Show eligibility criteria text
Inclusion Criteria: * Inclusion criteria: * Women with intramural fibroid without any cavity involvement * Age ˂ 35 years * I onCSI or IVF cycles * normal uterine cavity Exclusion Criteria: * Exclusion criteria: * low ovarian reserve (AFC \< 7 and or AMH \< 1.1 ng/ml) * Endometrioma * Untreated hydrosalpinx * Non obstructive azoospermia * Any other cavitary lesions (Asherman syndrome, Mullerian anomalies) * recurrent implantation failure
References
Publications (0)
Data not yet available
No reference posted for this study.