Clinical trial · Interventional
The Application of Indocyanine-Green(ICG) Fluorescence Imaging in Hepatocellular Carcinoma
NCT03793322CI-TRIAL-00036364unknownPhase 1ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study aims to evaluate the feasibility of indocyanine green (ICG)-based fluorescence imaging in the detection of liver tumors. By correlating the ICG fluorescence patterns with pathologically confirmed tumors , it would be possible to use fluorescence navigation system in helping promoting oncology treatment.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Hepatocellular Carcinoma | Hepatocellular Carcinoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Indocyanine-Green(ICG) | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Indocyanine-Green(ICG) injection group
- interventionNames
- Drug: Indocyanine-Green(ICG)
Primary outcomes (2)
- measure
- The accuracy of detecting small liver tumor by ICG fluorescence.
- timeFrame
- 3 Days
- description
- The tumor which aggregate ICG fluorescence will be resected and dignosed by pathology. The accuracy of detecting small liver tumor by ICG fluorescence will be evaluated.
- measure
- The accuracy of positive margins of resection detected by ICG fluorescence.
- timeFrame
- 3 Days
- description
- The surgery margins will be detected by ICG fluorescence. If there is fluorescence aggregating, we consider the presence of residual tumor in the margin and proven by histological examination.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * 18 years≤ Age ≤70 years * Compling with the diagnosis criteria of hepatic carcinoma. * Primary hepatic carcinoma without intrahepatic or extrahepatic extensive cancer metastasis, the metastatic hepatic carcinoma whose primary focal has been controlled. * Preoperative liver function is Child - Pugh grade A or B. * The patients are volunteered for the study. Exclusion Criteria: * Patients with mental illness. * Patients can't tolerate the operation owe to a variety of basic diseases (such as severe cardiopulmonary insufficiency, renal insufficiency, cachexia and blood system diseases, etc. * The patients refused to take part in the study. * There are other co-existed malignant tumors. * Benign liver diseases. * Indocyanine green allergy
References
Publications (0)
Data not yet available
No reference posted for this study.