Clinical trial · Interventional
Using Massage of Maxillofacial and Oral Cavity to Prevent Radioactive Oral Mucositis
Randomized, Controlled Clinical Study of Using Massage of Maxillofacial and Oral Cavity to Prevent Oral Mucositis in Patients With Nasopharyngeal Carcinoma Undergoing Radiotherapy
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
A total of 160 cases of nasopharyngeal carcinoma patients who met the inclusion criteria were randomly assigned to two groups. The experimental group was given massage of maxillofacial and oral cavity plus routine oral care and functional exercise. The control group was given routine oral care and functional exercise. Analyze the difference of incidence of severe acute radioactive oral mucositis in these two groups.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Nasopharyngeal Carcinoma | Nasopharyngeal Carcinoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Massage of Maxillofacial and Oral Cavity | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- NO_INTERVENTION
- label
- Control arm
- description
- routine oral care and functional exercise.
- type
- EXPERIMENTAL
- label
- Massage arm
- description
- Massage of Maxillofacial and oral cavity plus routine oral care and functional exercise
- interventionNames
- Other: Massage of Maxillofacial and Oral Cavity
Primary outcomes (1)
- measure
- Incidence of severe radioactive oral mucositis
- timeFrame
- 3 months
- description
- the status of oral mucosa was evaluated daily during radiotherapy. According to the grading standard of RTOG acute radiation injury, statistical analysis was made on whether there was a difference and statistical significance in the incidence rate of oral mucositis with radiation above grade 3 between the two groups.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: 1. Patients diagnosed by pathology with nasopharyngeal carcinoma; 2. ECOG PS: 0-2; 3. Gender is not limited, Age between 18 years old and 70 years old. 4. Clear consciousness, no mental illness or cognition impairment; 5. The expected survival time is more than 12 months; Exclusion Criteria: 1. Patients with other severe diseases affecting the quality of life or the treatment process; 2. Unwilling to actively cooperate with investigators; 3. Patients with previous oral diseases; 4. Patients who have received head and neck surgery and radiotherapy; 5. A history of psychotropic substance abuse or a mental disorder; 6. Participated in clinical trials of other anti-tumor drugs within 4 weeks before enrollment; 7. Women who are pregnant or in lactation; 8. Other situations that may affect the results of the clinical study.
References
Publications (0)
Data not yet available