Clinical trial · Observational
Preserving Left Colonic Artery During Radical Resection of Rectal Cancer
A Clinical Cohort Study on the Effect of Preserving Left Colonic Artery During Radical Resection of Rectal Cancer on Anastomotic Leakage and Oncology Efficacy
NCT03776370CI-TRIAL-00058229completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To evaluate the feasibility and clinical significance of preserving left colonic artery in rectal cancer surgery.The investigators will focus on the effect of preserving left colonic artery during radical resection of rectal cancer on anastomotic leakage and oncology efficacy.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Postoperative Complications | — | UNRESOLVED | — |
| Proteinosis | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Preserve the left colonic artery | Procedure | — | UNRESOLVED |
| The left colonic artery is not preserved | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Preserve the left colonic artery
- description
- Preservation of left colonic artery in rectal cancer surgery.
- interventionNames
- Procedure: Preserve the left colonic artery
- label
- The left colonic artery is not preserved
- description
- The left colonic artery was dissected in rectal cancer surgery
- interventionNames
- Procedure: The left colonic artery is not preserved
Primary outcomes (4)
- measure
- The incidence of postoperative anastomotic leakage was compared between the two groups.
- timeFrame
- Within 30 days after surgery
- description
- The incidence of anastomotic leakage within 30 days after surgery was compared between the intervention group and the control group.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: 1. Pathological biopsy confirmed adenocarcinoma of the rectum； 2. Preoperative assessment of tolerance to surgery without major organ dysfunction； 3. Patients must be able to understand and voluntarily sign written informed consent； 4. The surgical method is laparoscopic or robotic anterior rectal cancer resection. Exclusion Criteria: 1. The patient cannot tolerate the operation； 2. Refusal to sign informed consent； 3. Patients with distant metastasis of rectal cancer； 4. The surgical method was changed to miles or Hartman; 5. Unable to complete the follow - up
References
Publications (3)
- RESULTFan YC, Ning FL, Zhang CD, Dai DQ. Preservation versus non-preservation of left colic artery in sigmoid and rectal cancer surgery: A meta-analysis. Int J Surg. 2018 Apr;52:269-277. doi: 10.1016/j.ijsu.2018.02.054. Epub 2018 Mar 1. PMID 29501795
- RESULTSekimoto M, Takemasa I, Mizushima T, Ikeda M, Yamamoto H, Doki Y, Mori M. Laparoscopic lymph node dissection around the inferior mesenteric artery with preservation of the left colic artery. Surg Endosc. 2011 Mar;25(3):861-6. doi: 10.1007/s00464-010-1284-7. Epub 2010 Aug 20. PMID 20725744
- DERIVEDZheng H, Li F, Xie X, Zhao S, Huang B, Tong W. Preservation versus nonpreservation of the left colic artery in anterior resection for rectal cancer: a propensity score-matched analysis. BMC Surg. 2022 May 10;22(1):164. doi: 10.1186/s12893-022-01614-y. PMID 35538516