Metabolic Syndrome in Childhood Cancer Survivors

The research is devoted to studying the features of the metabolic syndrome in cancer survivors in childhood is supposed to answer the following questions: * How can metabolic syndrome be diagnosed in the Russian population of survivors of acute lymphoblastic leukemia and non-Hodgkin's lymphomas? * What are the features of the clinical symptoms of metabolic syndrome in this category of patients? * Which genetic mutations are found in cancer survivors of patients with metabolic syndrome; Which of these mutations can be considered as protective or vice versa predisposing to the development of metabolic syndromes? Is the metabolic syndrome associated with an increased frequency of toxic complications of therapy during the intensive stages?

Sex

All

Minimum age

5 Years

Maximum age

15 Years

Inclusion Criteria:

* Cancer survivors:
* Treatment with chemotherapy and/or radiation therapy for a primary ALL/NHL diagnosed prior to age 17 years.
* ≤ 15 years of age at the time of enrollment.
* No cytostatic drugs uptake during the study.

Exclusion Criteria:

* Diagnosis of diabetes mellitus types 1 or 2 types before antitumor therapy
* Active oncological disease
* History of allogeneic hematopoietic cell transplant
* The renouncement of participation from the patient or legally authorized representative