Clinical trial · Observational
Study of the Effect of Prehabilitation on Markers of Sarcopenia in Patients Undergoing Pancreatoduodenectomy for Malignant Disease
A Pilot Study of the Effect of Prehabilitation on Markers of Sarcopenia in Patients Undergoing Pancreatoduodenectomy for Malignant Disease
NCT03770117CI-TRIAL-00049478SIPUPcompletedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of this study is to assess whether prehabilitation supervised by an appropriate multimodality team improves indices of sarcopenia in patients scheduled to undergo pancreatoduodenectomy.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pancreatic Ductal Adenocarcinoma | Pancreatic Ductal Adenocarcinoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Prehabilitation | Procedure | — | UNRESOLVED |
| Standard Procedure | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Prehabilitation
- description
- In this arm of the study, participants will undergo prehabilitation prior to surgery. This is intended to increase the participants overall health prior to surgery to try and increase their general well-being during and after surgery. Prehabilitation is multimodal therapy comprising: 1. Assessment for malnutrition and nutritional support dependent on the outcome 2. Optimisation of management of pancreatic exocrine insufficiency 3. Assessment of muscle mass and strength 4. Individually tailored, goal directed exercise regimen under the care of physiotherapy
- interventionNames
- Procedure: Prehabilitation
- label
- Standard Procedure
- description
- In this arm, participants will not receive any Rehabilitation prior to the surgery. This is the current standard care and will act as the control data for this study.
- interventionNames
- Procedure: Standard Procedure
Primary outcomes (1)
- measure
- CT Scan Comparison
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 16 Years
- Maximum age
- 100 Years
Show eligibility criteria text
Inclusion criteria 1. Patients treated by pancreatic resection 2. Surgery for malignancy 3. Patients aged over 16 4. CT scans available for assessment Exclusion criteria 1. Patients scheduled for fast-track pancreatic resection as part of the jaundice pathway 2. Aged under 16 3. Patients not undergoing pancreatic resection
References
Publications (0)
Data not yet available
No reference posted for this study.