Clinical trial · Observational
Characterization of the Genetic Profile of Type 2 Endometrial Carcinoma in Martinique
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
In Martinique, about 33 new cases are diagnosed per year, with a high incidence rate of type 2 endometrial carcinoma which has a poor prognosis with few therapeutic options. Although targeted therapies are used in many types of cancer, they are still possible a minority of patients. In current practice, endometrial cancers do not benefit these therapies. Characterization of the molecular mechanisms involved in the genesis of type 2 endometrial carcinoma could help to identify biomarkers predictive of a response to targeted therapies. We propose to identify the genetic profile of type 2 endometrial carcinomas in Martinique.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Endometrial Neoplasms | Endometrial Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Intervention Arm | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Intervention Arm
- description
- Identify the genetic profile of type 2 endometrial carcinomas in Martinique from tumor sample for extraction of tumor DNA .
- interventionNames
- Diagnostic Test: Intervention Arm
Primary outcomes (1)
- measure
- Number of biomarkers identified by Next Generation Sequencing involved in type 2 endometrial tumors in Martinique
- timeFrame
- 24 Months
- description
- Characterization of potentially operable mutations in type 2 endometrial tumors from DNA sample withdraw at inclusion and during follow visit
Eligibility
Eligibility (as posted)
- Sex
- Female
Show eligibility criteria text
Inclusion Criteria: * Major subject living in Martinique with the following characteristics : * Patients with type 2 endometrial cancer, with anatomopathological confirmation * Affiliate or beneficiary of french social security. * Free, informed with a written consent signed by the participant and the investigator (at the latest on the day of inclusion and before any research required by the research). Exclusion Criteria: * Type 1 adenocarcinoma * Patients not affiliated to french social security * Refusal to participate.
References
Publications (0)
Data not yet available