Clinical trial · Interventional
Microwave Ablation Versus Liver Resection For Early Hepatocellular Carcinoma in Patients With Borderline Liver Function
NCT03766555CI-TRIAL-00063890unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
We propose a randomized controlled study to compare the treatment efficacy of microwave ablation to liver resection for hepatocellular carcinoma (HCC) in patients with borderline liver function.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Carcinoma, Hepatocellular | Hepatocellular Carcinoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Liver resection | Procedure | — | UNRESOLVED |
| Microwave ablation | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Microwave Ablation
- description
- Microwave ablation (MWA) will be performed in patients randomized to this arm.
- interventionNames
- Procedure: Microwave ablation
- type
- ACTIVE_COMPARATOR
- label
- Liver Resection
- description
- Liver resection will be performed in patients randomized to this arm.
- interventionNames
- Procedure: Liver resection
Primary outcomes (1)
- measure
- Overall survival
- timeFrame
- 5 years
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Age \>18 years * HCC amendable for both MWA and liver resection * Liver function of ALBI Grade 2 * Tumour size \</= 5cm * Absence of extrahepatic metastasis * Absence of radiology evidence of major vascular or bile duct invasion Exclusion Criteria: * Informed consent not available * Patients with ALBI 3, Child-Pugh B or above * Multifocal tumour * Presence of portal vein or hepatic artery thrombosis * Anticipation of concomitant procedures * Emergency hepatectomy * Ruptured HCC * Patients with chronic renal failure * Pregnant female patients
References
Publications (0)
Data not yet available
No reference posted for this study.