Clinical trial · Interventional
Acupressure for Fatigue in Ovarian Cancer Survivors
NCT03763838CI-TRIAL-00102485completedN/AResults postedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to see if accupressure can help reduce the severity of fatigue experienced by ovarian cancer patients. Acupressure involves applying mild to moderate physical pressure by fingers, hand or a device to specific points on the skin to try to bring about a change in the body's functioning, in this case relief from chronic fatigue.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Fatigue | — | UNRESOLVED | — |
| Ovarian Cancer | Malignant Ovarian Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Acupressure | Other | — | UNRESOLVED |
| Sham acupressure | Other | — | UNRESOLVED |
| Standard of Care | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- Acupressure plus standard of care
- description
- Using AcuWand, participants will apply acupressure to points that are known to affect physiology. Participants will also receive standard of care.
- interventionNames
- Other: Acupressure
- Other: Standard of Care
- type
- SHAM_COMPARATOR
- label
- Sham acupressure plus standard of care
- description
- Using AcuWand, participants will apply acupressure to points that are not known to affect physiology. Participants will also receive standard of care.
- interventionNames
- Other: Sham acupressure
- Other: Standard of Care
- type
- OTHER
- label
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 21 Years
Show eligibility criteria text
Inclusion Criteria: * Women aged 21 and older * Diagnosis of ovarian cancer, stages I to IV * Have average persistent fatigue defined a \>=4 on the Brief Fatigue Inventory. * Fatigue must have started at or after the diagnosis of ovarian cancer * Completed all primary cancer treatments (surgery, chemotherapy at least 6 months prior), except maintenance therapies * No other planned interventions for fatigue other than current stable medication Exclusion Criteria: * Medically unstable * Acupuncture or acupressure receipt in past year * Have a diagnosis of untreated mood disorder, e.g., bipolar or major depressive disorder * Have a current diagnosis of anemia * Have a current untreated diagnosis of hypothyroidism * Have an initiation, a cessation or change of treatment of any chronic medications, dietary supplements, behavioral therapy, physical therapy, etc., or any planned change of medications, supplements or therapies during the study * Have the possibility of becoming pregnant
References
Publications (2)
- DERIVEDZick SM, Chen D, Harris RE, Kruger G, Runyon A, Sen A, Snyder S, Pearce CL. Self-Acupressure for Fatigue in Patients Surviving Ovarian Cancer: A Randomized Clinical Trial. JAMA Netw Open. 2026 Feb 2;9(2):e2556357. doi: 10.1001/jamanetworkopen.2025.56357. PMID 41642626
- DERIVEDZick SM, Kruger G, Harte S, Sen A, Harris RE, Pearce CL. Acupressure for Cancer-fatigue in Ovarian Cancer Survivor (AcuOva) Study: A community-based clinical trial study protocol examining the impact of self-acupressure on persistent cancer-related fatigue in ovarian cancer survivors. Contemp Clin Trials. 2021 Aug;107:106477. doi: 10.1016/j.cct.2021.106477. Epub 2021 Jun 10. PMID 34119716