Clinical trial · Observational
Cardiovascular Function in Acute Leukemia
Cardiovascular Function in Leukemia Patients: an Observational Prospective Study
NCT03760237CI-TRIAL-00081466completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
An observational, prospective study to describe the rates and predictors of cardiovascular events in patients with acute leukemia.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| observation only | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Acute Leukemia
- description
- Observation only. Patients newly diagnosed with acute leukemia who are scheduled to start treatment with chemotherapy will be enrolled and followed serially with blood collection, echocardiogram, arterial applanation tonometry, and questionnaires for 1 year.
- interventionNames
- Other: observation only
Primary outcomes (1)
- measure
- Left Ventricular dysfunction
- timeFrame
- 1 year
- description
- defined as a reduction in Left Ventricular Ejection Fraction of more than 10 percentage points from baseline and to less than 50%.
Secondary outcomes (3)
- measure
- Incidence of Cardiovascular Events
- timeFrame
- 1 year
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 90 Years
Show eligibility criteria text
Inclusion Criteria: * Older than 18 years of age, * New diagnosis of untreated acute leukemia (prior treatment for myelodysplastic syndrome or myeloproliferative neoplams or prior treatment with an anthracycline for breast cancer, Hodgkin's lymphoma, non-Hodgkin's lymphoma or another diagnosis will be included). * Signed the informed consent form Exclusion Criteria: • Unable to provide informed consent
References
Publications (0)
Data not yet available
No reference posted for this study.