Clinical trial · Interventional
Aesthetic Reconstruction of Onco-surgical Mandibular Defects Using FFF With and Without CAD/CAM Customized Cutting Guide
Aesthetic Reconstruction of Onco-surgical Mandibular Defects Using Free Fibular Flap With and Without CAD/CAM Customized Osteotomy Guide (A Randomized Controlled Clinical Trial)
NCT03757273CI-TRIAL-00039702unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to compare Aesthetic results and operation time of free fibular flap with and without CAD/CAM customized osteotomy guide for reconstruction of mandibular defects.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Mandibular Tumors | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| FFF with CAD/CAM customized cutting guide | Procedure | — | UNRESOLVED |
| FFF without customized cutting guide | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- FFF with CAD/CAM customized cutting guide
- description
- Mandibular reconstruction using free fibular flap with CAD/CAM customized osteotomy guide.
- interventionNames
- Procedure: FFF with CAD/CAM customized cutting guide
- type
- ACTIVE_COMPARATOR
- label
- FFF without customized cutting guide
- description
- Mandibular reconstruction using free fibular flap without customized osteotomy guide. CAD/CAM 3D model for mandible will be used.
- interventionNames
- Procedure: FFF without customized cutting guide
Primary outcomes (1)
- measure
- Aesthetic
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * Patients affected by tumor involving Mandibular bone. Exclusion Criteria: * Patients having poor oncological prognosis * Patients with poor performance status together with other relative or absolute vascular contraindication. * Patients require marginal resection or with bilateral fibular fracture
References
Publications (1)
- DERIVEDAl-Sabahi ME, Jamali OM, Shindy MI, Moussa BG, Amin AA, Zedan MH. Aesthetic Reconstruction of Onco-surgical Mandibular Defects Using Free Fibular Flap with and without CAD/CAM Customized Osteotomy Guide: A Randomized Controlled Clinical Trial. BMC Cancer. 2022 Dec 2;22(1):1252. doi: 10.1186/s12885-022-10322-y. PMID 36460978