Clinical trial · Interventional
The Comparision of Minimally-invasive and Open Pancreaticoduodenectomy for Pancreatic Cancer
The Effect and Safety of Comparision Between Minimally-invasive and Open Pancreaticoduodenectomy for Pancreatic Cancer : A Randomized Prospective Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Minimally invasive pancreaticoduodenectomy remains one of the most challenging abdominal procedures. Safety and feasibility remain controversial when comparing minimally-invasive with open pancreaticoduodenectomy, especially for malignant tumors.The aim of this study was to compare minimally invasive and open pancreatoduodenectomy for short-term outcomes and long-term follow-up in a randomized trial.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pancreatic Carcinoma | Pancreatic Carcinoma | ONTOLOGY_EXACT | 0.98 |
| Surgery | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Minimally-invasive pancreaticoduodenectomy | Procedure | — | UNRESOLVED |
| Open pancreaticoduodenectomy | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Minimally-invasive Pancreaticoduodenectomy
- description
- MIPD
- interventionNames
- Procedure: Minimally-invasive pancreaticoduodenectomy
- type
- PLACEBO_COMPARATOR
- label
- Open Pancreaticoduodenectomy
- description
- OPD
- interventionNames
- Other: Open pancreaticoduodenectomy
Primary outcomes (4)
- measure
- Overall complications
- timeFrame
- Up to postoperative 30 days
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * Age: \>18yr, \<75yr * Patients with pancreatic cancer or non-pancreatic cancers (biliary duct cancer or ampullary cancer) who underwent pancreatoduodenectomy * Preoperative imaging assessment is resectable or borderline resectable Exclusion Criteria: * Benign tumors of the head of pancreas * Enhanced CT diagnosis revealed that the excess of SMV was more than 180 degrees, or distant metastasis. * conversion to laparotomy because of intraoperative difficulty
References
Publications (0)
Data not yet available