Clinical trial · Observational
Non-hypovascular Solid Pancreatic Lesions: Role of EUS
Role of EUS in Differential Diagnosis and Malignancy Prediction of Non-hypovascular Solid Pancreatic Lesions: A Prospective Observational Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Vascular pattern of solid pancreatic lesions (SPLs) has been investigated by different abdominal imaging modalities and by contrast-enhanced endoscopic ultrasonography (CE-EUS). Compared with surrounding pancreatic parenchyma three different patterns have been described: hypo-, iso-, and hypervascular. The majority of SPLs are hypovascular, and the diagnostic relevance of hypoenhanced pattern to predict pancreatic adenocarcinoma (PDAC) is well established. Differently, iso- and hypervascular pattern is not specific and can be expressed by several SPLs, with different clinical behavior and management. To date, poor is know about the role of EUS in differential diagnosis of non-hypovascular SPLs and features associated with malignancy.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Endoscopic Ultrasound | — | UNRESOLVED | — |
| Solid Pancreatic Neoplasms | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Endoscopic ultrasound-fine needle biopsy | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (3)
- measure
- Upstream dilation of the main pancreatic duct
- timeFrame
- 6 months
- description
- Percentage of cases with upstream dilation of main pancreatic duct will be recorded.
- measure
- Vascular pattern (iso or hypervascular)
- timeFrame
- 6 months
- description
- Percentage of cases with iso-vascular or hyper-vascular pattern will be recorded.
- measure
- Lesion borders (smooth or irregular)
- timeFrame
- 6 months
- description
- Percentage of cases with smooth or irregular borders will be recorded.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Presence of one or more solid pancreatic lesions preliminary evaluated by contrast-enhanced computed tomography (CE-CT) and/or contrast enhanced magnetic resonance imaging (CE-MRI) reporting a non-hypovascular contrast pattern (e.g., iso- or hypervascular). Exclusion Criteria: * Patients with associated chronic pancreatitis features (e.g., pancreatic calcifications) * Lesion with hypovascular pattern at CE-EUS. * Lesion not found or non pancreatic at EUS. * Patients refusing to be included in the study
References
Publications (0)
Data not yet available