Clinical trial · Interventional
Total Mesorectum Excision With Left Colic Artery Preservation for the Treatment of Rectal Cancer
A Randomized Controlled Clinical Trial to Investigate the Effects of Total Mesorectum Excision With Left Colic Artery Preservation for the Treatment of Rectal Cancer
NCT03724591CI-TRIAL-00035511unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
A randomized controlled clinical trial to compare the short and long term outcomes of left colic artery preservation for the treatment of Rectal Cancer
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Rectal Cancer | Malignant Rectal Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| a high ligation of IMA | Procedure | — | UNRESOLVED |
| a low ligation of IMA | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- a high ligation of IMA
- description
- total mesorectal excision (TME) for rectal cancer by a high ligation of IMA without preservation of left colic artery
- interventionNames
- Procedure: a high ligation of IMA
- type
- ACTIVE_COMPARATOR
- label
- a low ligation of IMA
- description
- total mesorectal excision (TME) for rectal cancer by a low ligation of IMA with preservation of left colic artery
- interventionNames
- Procedure: a low ligation of IMA
Primary outcomes (1)
- measure
- Anastomosis leakage rate
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 85 Years
Show eligibility criteria text
Inclusion Criteria: * Patients suitable for curative surgery over 18 years old; * American Society of Anesthesiologists(ASA) grade I-III; * Pathological diagnosis of rectal adenocarcinoma; * Patients suitable for abdominalperineal resection * Informed consent; * No history of familial adenomatous polyposis, ulcerative colitis or Crohn's disease. Exclusion Criteria: * Pregnant patient; * History of psychiatric disease; * Use of systemic steroids; * Simultaneous multiple primary colorectal cancer; * Preoperative imaging examination results show:1. Tumor involves the surrounding organs and combined organ resection need to be done;2. distant metastasis;3. unable to perform R0 resection; * History of any other malignant tumor in recent 5 years; * Patients need emergency operation: mechanic ileus, perforation.
References
Publications (0)
Data not yet available
No reference posted for this study.