Clinical trial · Interventional
Smartphone Technology to Alleviate Malignant Pain (STAMP)
Smartphone Technology to Alleviate Malignant Pain (STAMP): Development and Piloting of a Novel mHealth Intervention to Support Cancer Patients, Nurses, and Physicians in Opioid Management
NCT03717402CI-TRIAL-00066900completedN/AResults postedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of the study is to develop the STAMP app (Smartphone Technology to Alleviate Malignant Pain). This app will be used by patients with advanced cancer to track symptoms and receive tailored symptom management advice. This is a single arm pilot feasibility study of the application among patients with advanced cancer and chronic pain who are using opioids in the home setting. Patients will be asked to use the application for a four week period. Clinicians responsible for the patients' pain management will be asked to review alerts from the STAMP system and respond accordingly. The primary outcomes of the study relate to feasibility and acceptability.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| Opioid Use | — | UNRESOLVED | — |
| Pain Management | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Intervention Participants | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- OTHER
- label
- Intervention Participants
- description
- Patients with advances cancer using opioids for chronic pain will be enrolled and asked to use the STAMP cancer pain management app for 4 weeks.
- interventionNames
- Behavioral: Intervention Participants
Primary outcomes (2)
- measure
- Frequency of Patient Log Ins
- timeFrame
- 4 Weeks
- description
- We will calculate the frequency that patients log in to the application using simple descriptive statistics.
- measure
- Frequency of Symptom Survey Completion
- timeFrame
- 4 weeks
- description
- We will calculate the number of times patients completed a symptom survey on app during their 28 days on study. Patients could complete up to one symptom survey per day on study.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 21 Years
Show eligibility criteria text
Inclusion Criteria: Patient Inclusion Criteria: * Patient is cared for within participating clinic (PC) * Age ≥21 * Diagnosed with locally advanced, metastatic solid tumor, or multiple myeloma being managed with palliative intent * Chronic pain related to cancer or cancer treatment, persisting or at least two weeks * Average pain rating of ≥4/10 currently, or at least one day within the past week * Active prescription for short and/or long acting opioids * Takes at least 1 opioid medication on most days * Own a compatible smartphone: * iPhone, have updated or willing to update it to the past 3 iOS version releases * Android flagship devices with more than 5% market share, last 2 android version releases Clinician Inclusion Criteria: * Physicians and mid-level providers practicing in participating clinics and caring for a patient on the study * Nurse Navigators working within participating clinics Exclusion Criteria: Patient Exclusion Criteria: * Cognitive impairment that would interfere with study participation, as judged by treating clinician * Inability to speak English * History of opioid use disorders * Enrolled in hospice * Currently hospitalized * Use of opioids not supported by STAMP * Pain primarily related to a recent surgery * Currently has or has had recurrent bowel obstructions * The following special populations are excluded: adults unable to consent, prisoners, and pregnant women. Clinician Exclusion Criteria: \- Unwilling to participate
References
Publications (8)
- BACKGROUNDvan den Beuken-van Everdingen MH, Hochstenbach LM, Joosten EA, Tjan-Heijnen VC, Janssen DJ. Update on Prevalence of Pain in Patients With Cancer: Systematic Review and Meta-Analysis. J Pain Symptom Manage. 2016 Jun;51(6):1070-1090.e9. doi: 10.1016/j.jpainsymman.2015.12.340. Epub 2016 Apr 23. PMID 27112310
- BACKGROUNDDalal S, Bruera E. Access to opioid analgesics and pain relief for patients with cancer. Nat Rev Clin Oncol. 2013 Feb;10(2):108-16. doi: 10.1038/nrclinonc.2012.237. Epub 2013 Jan 15. PMID 23319138
- BACKGROUNDJadad AR, Browman GP. The WHO analgesic ladder for cancer pain management. Stepping up the quality of its evaluation. JAMA. 1995 Dec 20;274(23):1870-3. PMID 7500538
- BACKGROUNDDeandrea S, Montanari M, Moja L, Apolone G. Prevalence of undertreatment in cancer pain. A review of published literature. Ann Oncol. 2008 Dec;19(12):1985-91. doi: 10.1093/annonc/mdn419. Epub 2008 Jul 15. PMID 18632721
- BACKGROUNDBreivik H, Cherny N, Collett B, de Conno F, Filbet M, Foubert AJ, Cohen R, Dow L. Cancer-related pain: a pan-European survey of prevalence, treatment, and patient attitudes. Ann Oncol. 2009 Aug;20(8):1420-33. doi: 10.1093/annonc/mdp001. Epub 2009 Feb 24. PMID 19244085
- BACKGROUNDCleeland CS, Gonin R, Hatfield AK, Edmonson JH, Blum RH, Stewart JA, Pandya KJ. Pain and its treatment in outpatients with metastatic cancer. N Engl J Med. 1994 Mar 3;330(9):592-6. doi: 10.1056/NEJM199403033300902. PMID 7508092
- BACKGROUNDTariman JD, Berry DL, Halpenny B, Wolpin S, Schepp K. Validation and testing of the Acceptability E-scale for web-based patient-reported outcomes in cancer care. Appl Nurs Res. 2011 Feb;24(1):53-8. doi: 10.1016/j.apnr.2009.04.003. Epub 2009 Sep 18. PMID 20974066