Clinical trial · Interventional
Ultra-High Resolution Optical Coherence Tomography in Detecting Micrometer Sized Early Stage Pancreatic Cancer in Participants With Pancreatic Cancer
Imaging and Detection of Micrometer Sized Early Stage Pancreatic Cancer by Using Endoscopic Ultra-High Resolution Optical Coherence Tomography (OCT) Using Resected Pancreatic Specimen, a Pilot Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This trial studies how well ultra-high resolution optical coherence tomography works in detecting micrometer sized early stage pancreatic cancer in participants with pancreatic cancer. Ultra-high resolution optical coherence tomography may help to accurately identify pancreatic cancer in resected pancreatic specimens.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pancreatic Carcinoma | Pancreatic Carcinoma | ONTOLOGY_EXACT | 0.98 |
| Pancreatic Intraductal Papillary Mucinous Neoplasm, Pancreatobiliary-Type | Pancreatic Intraductal Papillary Mucinous Neoplasm, Pancreatobiliary-Type | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Laboratory Evaluation | Diagnostic Test | — | UNRESOLVED |
| Optical Coherence Tomography | Procedure | — | UNRESOLVED |
| Therapeutic Conventional Surgery | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Diagnostic (resection, OCT)
- description
- Participants undergo resection. Resected tissues are analyzed via ultra-high resolution OCT.
- interventionNames
- Procedure: Optical Coherence Tomography
- Procedure: Therapeutic Conventional Surgery
- Diagnostic Test: Laboratory Evaluation
Primary outcomes (1)
- measure
- Measure accuracy of using OCT to diagnose pancreatic cancer and compare with histology.
- timeFrame
- Up to 3 years
- description
- Will evaluate the accuracy of the optical coherence tomography (OCT) based diagnosis compare to the pathological diagnosis or the cancer cell derived exosomes test from the blood sample. Will compare the diagnosis results from the OCT imaging technology to standard histopathologic assessment and the blood test using 2-way tables. The agreement between two tests will be summarized with the overall agreement and the Cohen?s Kappa values.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Immediate surgery cohort: Adult patients with pancreatic cancer or IPMN * Immediate surgery cohort: Informed consent will be obtained * Adult patients undergoing pancreatic resection for a presumed IPMN Exclusion Criteria: * Pregnant
References
Publications (0)
Data not yet available