Clinical trial · Interventional
Effect of Anesthetic Agents on Optic Nerve Sheath Diameter
Effect of Anesthetic Agents (Propofol, Sevoflurane) on Optic Nerve Sheath Diameter(ONSD) in Patients Undergoing Robot-assisted Laparoscopic Gynecology Surgery
NCT03701529CI-TRIAL-00046967completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The present study is to evaluate the effect of anesthetic agents ( propofol , sevoflurane) on intracranial pressure of female patients undergoing laparoscopic-robotic surgery.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Uterine Cancer | Malignant Uterine Neoplasm | ALIAS | 0.90 |
| Uterus Myoma | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Propofol | Drug | — | UNRESOLVED |
| Sevoflurane | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Sevoflurane
- description
- 1.5-2.5 vol% of sevoflurane is used for maintenance of anesthesia.
- interventionNames
- Drug: Sevoflurane
- type
- ACTIVE_COMPARATOR
- label
- Propofol
- description
- 2-5 mcg/ml of propofol is used continuously for maintenance of anesthesia using target-controlled infusion system.
- interventionNames
- Drug: Propofol
Primary outcomes (1)
- measure
- difference of optic nerve sheath diameter
- timeFrame
- During the operation.
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: * female patients undergoing robot-assisted laparoscopic hysterectomy or myomectomy Exclusion Criteria: * history of brain hemorrhage or brain infarction * liver disease or end stage renal disease * glaucoma or any signs of increased intraocular pressure * combined wtih other types of operation * patient refusal * weight less than 40 kg or over 100 kg
References
Publications (0)
Data not yet available
No reference posted for this study.